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《常州市国家级麻疹监测点武进区正常人群麻疹抗体水平监测分析.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、实用预防医学2013年12月第20卷第12期PracticalPreventiveMedicine,Dec.2013,Vol20,No.121447文章编号:1006—3110(2013)12—1447—03·疾病控制·常州市国家级麻疹监测点武进区正常人群麻疹抗体水平监测分析薛京昌,卞琛,徐晓怡摘要:目的了解常州市国家级麻疹监测点2009—2012年正常人群麻疹抗体水平监测情况,为确定麻疹易感者及其免疫策略提供依据。方法采集常州市武进区0-、1~、3~、5~、7~、10~、15~、≥20岁共八个年龄组血清1612份,用酶联免疫吸附试验检测麻疹IgG。结果人群麻疹IgG抗体阳性率为89.33%,
2、几何平均浓度(IC)为1617.37mIU/rnl。四年间GMC两两比较差异均有统计学意义。不同年龄组人群的麻疹IgG抗体阳性率为49.50%~99.01%,差异有统计学意义(=429.82,P<0.001),不同年龄组GMC为697.07~1432.76mIu/ml,差异有统计学意义(F=7.998,P<0.001)。结论继续加强免疫规划管理力度,结合麻疹疫情对一定年龄的人群实行强化免疫。关键词:麻疹;抗体水平;监测中图分类号:R511.1文献标识码:BDOI:10.3969/j.issn.1006—3110.2013.12.013AnalysisontheMonitoringSituati
3、onofMeaslesAntibodyLevelsAmongNormalPopulationinNationalMeaslesSurveillancePointsinWujinDistrict,ChangzhouXUEJing—chang,BIANChen,XUXiao—yi(ChangzhouMunicipalCenterforDiseaseControlandPvention,Changztmu213022,Jiangsu,China)Abstract:ObjectiveToinvestigatethemonitoringsituationofmeaslesantibodylevelsof
4、normalpopulationinnationalmeaslessurveillancepointsinChangzhoufrom2009to2012SOastoprovideevidenceforidentifyingperSOnssusceptibletOmeaslesandformulatingimmunizationstrategies.MethodsWecollected1,612serumsamplesfrom8agegroupsinWujinDistrict,ChangzhouCity.Enzyme—linkedimmunosorbentassayWasusedtodetect
5、thelevelsofmeaslesimmunoglobulinG(Ig6)anti—bodies.ResultsThepositiverateofmeaslesIgGantibodyWas89.33%,andthegeometricme.q_concentration(GMC)Was1,617.37mIU/m1.PairwisecompariSOnshowedthattherewerestatisticallysignificantdifferencesinGMCamongthefouryears.ThepositiveratesofmeaslesIgGantibodyindifferent
6、agegroupswere49.50%一99.01%.andthedifferenceWasstatis—ticallysignificant(;(=429.82,P<0.001).GMCsofdifferentagegroupswere697.07—1,432.76mIU/ml,andthediffer—enceWasstatisticallysignificant(F=7.998,P<0.001).ConclusionsItisnecessarytoconstantlystrengthenthemanage—mentofimmunizationpmgrarnandimplementsupp
7、lementaryimmunizationamongthesusceptibleperSOnsbasedonmeaslesepi—demic.Keywords:Measles;Antibody1evd;Monitoring麻疹是由呼吸道麻疹病毒引起急性呼吸道传染病,传染性3-、5~、7~、10~、15~、≥20岁,8个年龄组中各抽取50~52极强。了解和掌握相关人群的麻疹抗体水平,对预测麻疹的流名
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