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1、CT引导下射频消融联合同步放化疗治疗局部晚期非小细胞肺癌的临床观察【摘要】目的：探讨CT引导下射频消融联合同步放化疗治疗晚期非小细胞肺癌的临床疗效。方法：选择本院2014年9月-2015年1月收治的80例局部晚期非小细胞肺癌患者为研究对象，将其随机分为两组，对照组40例，研究组40例，对照组行传统同步放化疗治疗，研究组行CT引导下射频消融联合同步放化疗治疗，对两组患者治疗结果进行分析。结果：两组患者治疗前KPS评分无明显差（P>0.05）,经治疗后，观察组明显优于对照组，差异有统计学意义（P<0.05）；观察组患者治疗3个月后复查CT,有效率显著高于对照组（P<
2、0.05）,CT影像显示肺内肿瘤体积明显缩小甚至消失。结论：CT引导下射频消融联合同步放化疗对局部晚期非小细胞肺癌患者进行治疗，能有效消除肿瘤，效果显著，有利于患者远期预后，值得临床进一步推广使用。【关键词】CT引导下射频消融；同步放化疗；晚期非小细胞肺癌TheClinicalObservationontheTreatmentforNon-smallCel1LungCancerwithConcurrentRadiochemotherapyCombinedwithRadiofrequencyAblationGuidedbyCT/ZHENGQiao~cong,ZHA
3、NGQi-hong,A0Yong-xi,etal.//MedicalInnovationofChina,2015,12（16）：078-080[Abstract]Objective：Toprobeintotheclinicaleffectsofthetreatmentfornon~smallcelllungcancerwithchemoradiationcombinedwithradiofrequencyablationguidedbyCT.Method:80patientswhosufferedfromthenon-smallcelllungcancerand
4、whoacceptedtreatmentsinourhospitaifromSeptember2014toJanuary2015weretakenastheresearchobjects,andthesepatientswererandomlydividedintothecontrolgroupandtheobservationgroup,with40patientsineachgroup.Inthecontrolgroup,theyweretreatedwiththetraditionalmethodofconcurrentradiochemotherapyw
5、hiletheobservationgroupweretreatedwiththechemoradiationcombinedwithradiofrequencyablationguidedbyCT.Then,thetreatment,effectsofthesetwogroupsofpatientswereanalyzed.Result：Beforethetreatments,theKPSscoreofthesetwogroupsofpatientsdidnothaveevidentdifference(P>0.05).However,afterthetrea
6、tments,theobservationgroupwasevidentlybetterthanthecontrolgroupandthedifferenceshadthestatisticalsignificance(P<0.05).Inaddition,accordingtotheresultofthecheckwithCTthreemonthslater,theefficiencyrateintheobservationgroupwasevidentlyhigherthanthatinthecontrolgroup(P<0>05).Conclusion：T
7、hetreatmentfornon-smal1cel1lungcancerwithchemoradiationcombinedwithradiofrequencyablationguidedbyCTcaneffectivelygetridoftumorsandcanbegoodforthelong-termprognosisofpatients,whichshouldbepromotedintheclinicalapplication.［Keywords］RadiofrequencyablationguidedbyCT；Concurrentradiochemot
8、herapy；Non-s
