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时间:2020-05-23
《近红外波辅助治疗慢性乙型肝炎及肝硬化临床疗效评价.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、·论著·25近红外波辅助治疗慢性乙型肝炎及肝硬化临床疗效评价高庆伟,尚浩,周伟,韩光,伍艳玲(大连市第六人民医院,大连116031)摘要:目的探讨近红外波辅助治疗慢性乙型肝炎(CHB)及乙型肝炎后肝硬化的临床疗效。方法选择CHB患者54例,随机分为治疗组与对照组(各27例);肝硬化患者12例,随机分为治疗组与对照组(各6例)。对照组应用抗病毒药物和保肝药物治疗,治疗组在对照组治疗基础上使用近红外波治疗,比较两组治疗效果。结果两组CHB患者实际住院天数,症状改善时间差异均有统计学意义(尸=O.041、0.015);治疗后丙氨酸氨基转移酶(ALT)复常差异无统计学意义(尸=0.082);治疗后
2、白细胞(WBC)、血红蛋白(HB)、乙型肝炎病毒表面抗原(HBsAg)比较,差异均无统计学意义(P=0.560、0.471、0.520)。治疗组CHB患者血小板(PLT)显著高于对照组(P=0.001)。乙型肝炎后肝硬化患者治疗组实际住院天数、ALT与对照组比较,差异均有统计学意义(JP=0.021、0.023);治疗后症状改善时间与对照组比较,差异无统计学意义(尸=0.075);治疗后WBC、HB、HBsAg比较,差异均无统计学意义(P=0.721、0.562、0.895)。治疗组肝硬化患者治疗后PLT数量与对照组比较,差异有统计学意义(P=0.012)。结论近红外波辅助治疗乙型肝炎及肝
3、硬化患者具有一定的临床疗效,可作为乙型肝炎及肝硬化患者的辅助治疗手段。关键词:肝炎,乙型;肝硬化;近红外线Evaluationonclinicalefectofnear-infraredwaveintreatmentofpatientswithchronichepatitisBandcirrhosisGAOQing—wei,SHANGHao,ZHOUWei,HANGuang,wuYan·ling(TheSixthPeopleHospitalofDalian,DaBan116031,China)Abstract:ObjectiveToevaluatetheclinicalefectofnea
4、r-infraredwaveintheassistedtreatmentofchronichepatitisBandassociatedcirrhosis.MethodsTotalof54caseswithchronichepatitisBwererandomlydividedintotwogroups,27casesineachgroup;12patientswithcirrhosiswererandomlydividedintotwogroups,6casesineachgroup.Patientsintwogroupsweregiventheantiviralandhepatopro
5、tectivetreatment,andpatientsintreatmentgroupwerealsoappliedwimnear-infraredwaveatthesalnetime.theeficacyofthetwogroupswereanalyzed.ResultsForchronichepatitisBpatients,thepedodsofhospitalizationandsymptomimprovementbetweenthetreatmentgroupandcontrolgroupweresignificantlydiferent=O.041,0.015)butther
6、eisnosignificantdiferenceonperiodofALTrecoveryrP=0.082);aloswithsignificantdiferencesinwhitebloodceilscount,hemoglobinconcentration,HBsAgtiter(P=0.560,0.471,0.520);andtheplateletwassignificantlyhigherafterintreatmentgroup(尸=0:001).Forcirhosispatients,thegrouptreatedwithnear-infraredwavewascompared
7、withthecontrolgroup,thereweresignificantdiferencesintheperiodsofhospitalizationandALTrecovery(尸=0.021,0.023);alsowithsignificantdiferencesinwhitebloodcellscount,hemoglobinconcentration,HBsAgtiter=O.721,0.562,0.89
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