血清尿酸和超敏C反应蛋白水平在稳定型心绞痛患者病情监测中的临床意义-论文.pdf

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1、实用临床医药杂志2014年第18卷第15期·122·JournalofClinicalMedicineinPractice血清尿酸和超敏C反应蛋白水平在稳定型心绞痛患者病情监测中的I临床意义张利英(河北省秦皇岛市第二医院心内科，河北秦皇岛，066600)摘要：目的回顾性研究稳定型心绞痛患者血清尿酸(uA)和超敏C反应蛋白(hs—CRP)监测的意义。方法对146例稳定型心绞痛患者的uA和hs-CRP水平进行检测，随访观察，1年后根据病情发展情况分为稳定组98例和进展组48例，检测2组的【JA和hs-CRP水平，

2、另选取健康体检者作为对照组，检测UA和hs-CRP水平，对比分析。结果初查时，稳定组及进展组患者uA和hs-CRP的水平显著高于对照组(P<0．O1)；进展组患者UA和hs-CRP的水平显著高于稳定组(P<0．01)。复查后发现，稳定组患者复查后uA和hs-CRP的水平与初查时比较有增高趋势，但无显著差异(P>O．05)；进展组患者傅查后UA和hs-CRP的水平显著高于初查时结果(P<0．O1)；进展组患者UA和hs-CRP的水平显著高于稳定组(P<0．01)。结论稳定型心绞痛患者血清UA和hsCRP水平与病

3、情发展和预后密切相关，检测此2项指标有利于了解病情严重程度，以做早期积极处理。关键词：稳定型心绞痛；血清尿酸；血清超敏c反应蛋白；病情监测中图分类号：R541文献标志码：A文章编号：1672—2353(2014)15—122—03D()I：10．7619／]cmp．201415041ClinicalsignificanceofserumuricacidandhypersensitiVityC—reactiveproteininmonitoringtheconditionsofpatientswithstabl

4、eanginapectorisZHANGLiying(DepartmentofCardiology，TheSecondHospitalofQinhuangdao，Qinhuangdao，Hebei，066600)ABSTRACT：0bjectiveToretrospectivelyanalyzetheclinicalsignificanceofserumuricacid(UA)andhypersensitivityC—reactiveprotein(hs—CRP)inmonitoringtheconditio

5、nsofpatientswithstableanginapectoris(SAP)．MethodsSerumUAandhs—CRPlevelsinSAPpatientsweredetected，andweredividedintostablegroup(98cases)andprogressivegroup(48cases)after卜yearfollowupandobservation．SerumUAandhs—CRPlevelsweredetectedinbothgroups．Andanother50he

6、althypeoplewereselectedascontrolgrouptocomparetheserumUAandhs—CRPlev—els．ResultsInprimaryinvestigation，serumUAandhs—CRPlevelsinstableandprogressivegroupswereevidentlyhigherthanincontrolgroup(P<0．01)，andwereobviouslyhigherinprogressivegroupthaninstablegroup(

7、P<0．01)．Afterre—examination，theyhadslightincreaseinstablegroupthaninprimaryinvestigation，butthedifferencewasnotsignificant(P>0．05)．However，theyweremarkedlyhigherinprogressiveafterre——examinationthaninprimaryinvestigationandsta—blegroup(P<0．01)．ConclusionSer

8、umUAandhs—CRPlevelsinpatientswithSAParecloselyassociatedwiththedevelopmentandprognosisofSAP，whosedetectionsarehelpfulininvestigatingdiseaseseverityandconductearlytreatment．KEYWORDS：stableanginapectoris