梧州市331例麻疹疑似患者血清检测结果分析.pdf

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1、第32卷第3期国外医学医学地理分册Vo1．32No．32011年9月F0REIGNMEDICALSCIENCESECTIoN0FMEDGEOGRAPHYSep．2011‘199‘梧州市331例麻疹疑似患者血清检测结果分析郭永强，卢家友，谭春柳(梧州市疾病预防控制中心，广西梧州543002)摘要：目的了解梧州市2005～2010年麻疹疫情的流行特征，排除临床麻疹疑似病例中的风疹患者等其他出疹性疾病，为制定预防控制麻疹提供科学依据。方法采用酶联免疫捕获法对疑似麻疹患者血清进行麻疹IgM抗体检测，同时检测风疹IgM抗体。结果2005~2010年共收检梧州各市县送检疑似麻疹患者血

2、清331份，麻疹IgM抗体阳性66例，阳性率为19．94；风疹IgM抗体阳性96例，阳性率为29．00；麻疹IgM抗体和风疹IgM抗体均阳性3例，占总数的0．91％。麻疹发病年龄构成呈两极趋势，发病率以26岁以上年龄组最高，阳性率为41．18；萁次为8月龄以下组，阳性率为31．25；1O～15岁组麻疹发病率最低，阳性率为7．44，麻疹疑似病例中，经实验室确诊为风疹发病率却最高，阳性率为42．98；其他出疹性病例占51．o6。结论继续做好麻疹疫苗的常规免疫工作，提高麻疹疫苗初免及时接种率。同时加强流动人口管理工作。麻疹的实验室诊断必须同时进行风疹等出疹性疾病实验室检测，以排

3、除临床误诊。关键词：麻疹；风疹；IgM抗体中图分类号：R511．1文献标志码：A文章编号：1001—8883(2011)03-0199—03Analysisoftheserumtestingresultsof331suspectedpatientswithmeaslesinWuzhouCityGUOYong—qiang，LUJia—you，TANChun—liu(WuzhouMunicipalityCenterforDiseaseControlandPrevention，Wuzhou543002，China)ABSTRACT：0bjectiveTolearnaboutth

4、eepidemicfeaturesofthemeaslesinWuzhoucityfrom2005to2010，andeliminatetherubellameaslesandotherrashcasesfromthemeaslespatients，soastoprovidescientificevidencesformeaslespreventionandcontro1．MethodsELISAmethodwasadoptedtotesttheIgManti-bodiesofpatientswithmeaslesandtheIgManti-bodiesofrashpat

5、ientsaswel1．ResultsAmong331samplesofthesuspectedpatientswithmeaslescollectedfrommunicipalandcountylevelsinWuzhou，66patientswerepositivewithIgMmeaslesantibodies，withthepositiveratio19．94；96patientswerepositivewithIgMrashantibodies，withthepositiveratio29．00；3patientswerepositivebothwithIgMm

6、easlesantibodies，andIgMrashantibodies，0．91ofthetotalcases．Theagedistributionofthepatientswithmeasleswereradicalwiththehighestincidenceratioamongthepatientsabove26，withpositiveratio41．18，andthenextisundertheageof8months；thepatientsfrom10to25yearsoldwerewiththelowestincidence，withpositivera

7、tio7．44．Amongthesuspectedpatientswithmeasles，therashincidenceratioofthelaboratoryidentifiedcaseswasthehighest，withpositiveratio42．98，andotherrashcaseswere51．O6％．ConclusionItisadvisabletocarryouttheroutinemeaslesvaccinationandthetimelyvaccinationofthefirstmeaslesimmu