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时间:2020-05-15
《燃煤型氟中毒对雌鼠血细胞的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、59O重庆医学2015年2月第44卷第5期论著·基础研究doi:10.3969/j.issn.1671—8348.2015.05.005燃煤型氟中毒对雌鼠血细胞的影响王世君,谢婷婷。,夏曙华,周进。,余司文,徐静峰,崔淼淼(1.贵阳医学院附属医院临床检验科,贵阳550004;2.贵阳医学院检验学院临床检验教研室,贵阳550004;3.贵阳医学院附属医院乌当医院检验科,贵阳550004;4.上海市闸北区中心医院检验科200070;5.贵州省贵阳市第二人民医院外科550000;6.贵州省贵阳市第二人民医院检验科550000)摘要:目的探讨不同染氟剂量在不同时间对雌鼠血细胞的影
2、响。方法选用SD雌性大鼠按体质量分为对照组(饲以非病区玉米饲料,含氟量为5.2mg/kg)、中氟组、高氟组(饲以掺入燃煤型氟中毒病区玉米饲料,含氟量分别为47.8、96mg/kg),中氟组、高氟组合称染氟组。于染氟60、120、180d进行血常规检测。结果染氟60、120d高氟组白细胞(WBC)较中氟组明显减少(P3、低(P<0.05),第180天时染氟组MCV反而有增高趋势(P4、细胞;燃煤型氟中毒;SD雌鼠中图分类号:R599文献标识码:A文章编号:1671-8348(2015)05—059O03Effectsofcoal‘buringcausedfluorosisonbloodcellsoffemaleSDratsWangShijun,XieTingting,XiaShuhua’,ZhouJin。,YuSiwen,XuJingfeng,CuiMiaomiao(1.Departmento/ClinicalLaboratory,theAffiliatedHospitalo/’GuiyangMedicalCollege,Guiyang,Guizhou5、550004,China;2.ClinicalTeachingandResearchSection,InstituteofInspection,CruiyangMedicalCollege,Ouiyang,Guizhou550004,China;3.DepartmentofClinicalLaboratory,TheA/filiatedWudangHospitalo/GuiyangMedicalCollege,Guiyang,Guizhou550004,China;4.DepartmentofClinicalLaboratory,ShanghaiZhabeiCentrlH6、ospital,Shanghai200070,China;5.DepartmentofSurgery,GuiyangSecondPeoplesHospital,Cruiyang,Guizhou550000,China;6.DepartmentofClinicalLaboratory,GuiyangSecondPeopleHospital,Cmiyang,Guizhou550000,China)Abstract:0bjectiveTostudytherelationshipbetweenthecompletebloodcount(CBC)andcoal—buringcaus7、edfluorosisoffe—malerats.MethodsFemaleSDratswererandomlydividedintothreegroups:controlgroup,medium—fluorinegroupandhigh—fluo—rinegroup.Ratsineachexposedgroupwerefedwithfoddercontainingdifferentproportionsofcorndriedbyburningcoalfromflu—orosisendemicareastoestablishc
3、低(P<0.05),第180天时染氟组MCV反而有增高趋势(P4、细胞;燃煤型氟中毒;SD雌鼠中图分类号:R599文献标识码:A文章编号:1671-8348(2015)05—059O03Effectsofcoal‘buringcausedfluorosisonbloodcellsoffemaleSDratsWangShijun,XieTingting,XiaShuhua’,ZhouJin。,YuSiwen,XuJingfeng,CuiMiaomiao(1.Departmento/ClinicalLaboratory,theAffiliatedHospitalo/’GuiyangMedicalCollege,Guiyang,Guizhou5、550004,China;2.ClinicalTeachingandResearchSection,InstituteofInspection,CruiyangMedicalCollege,Ouiyang,Guizhou550004,China;3.DepartmentofClinicalLaboratory,TheA/filiatedWudangHospitalo/GuiyangMedicalCollege,Guiyang,Guizhou550004,China;4.DepartmentofClinicalLaboratory,ShanghaiZhabeiCentrlH6、ospital,Shanghai200070,China;5.DepartmentofSurgery,GuiyangSecondPeoplesHospital,Cruiyang,Guizhou550000,China;6.DepartmentofClinicalLaboratory,GuiyangSecondPeopleHospital,Cmiyang,Guizhou550000,China)Abstract:0bjectiveTostudytherelationshipbetweenthecompletebloodcount(CBC)andcoal—buringcaus7、edfluorosisoffe—malerats.MethodsFemaleSDratswererandomlydividedintothreegroups:controlgroup,medium—fluorinegroupandhigh—fluo—rinegroup.Ratsineachexposedgroupwerefedwithfoddercontainingdifferentproportionsofcorndriedbyburningcoalfromflu—orosisendemicareastoestablishc
4、细胞;燃煤型氟中毒;SD雌鼠中图分类号:R599文献标识码:A文章编号:1671-8348(2015)05—059O03Effectsofcoal‘buringcausedfluorosisonbloodcellsoffemaleSDratsWangShijun,XieTingting,XiaShuhua’,ZhouJin。,YuSiwen,XuJingfeng,CuiMiaomiao(1.Departmento/ClinicalLaboratory,theAffiliatedHospitalo/’GuiyangMedicalCollege,Guiyang,Guizhou
5、550004,China;2.ClinicalTeachingandResearchSection,InstituteofInspection,CruiyangMedicalCollege,Ouiyang,Guizhou550004,China;3.DepartmentofClinicalLaboratory,TheA/filiatedWudangHospitalo/GuiyangMedicalCollege,Guiyang,Guizhou550004,China;4.DepartmentofClinicalLaboratory,ShanghaiZhabeiCentrlH
6、ospital,Shanghai200070,China;5.DepartmentofSurgery,GuiyangSecondPeoplesHospital,Cruiyang,Guizhou550000,China;6.DepartmentofClinicalLaboratory,GuiyangSecondPeopleHospital,Cmiyang,Guizhou550000,China)Abstract:0bjectiveTostudytherelationshipbetweenthecompletebloodcount(CBC)andcoal—buringcaus
7、edfluorosisoffe—malerats.MethodsFemaleSDratswererandomlydividedintothreegroups:controlgroup,medium—fluorinegroupandhigh—fluo—rinegroup.Ratsineachexposedgroupwerefedwithfoddercontainingdifferentproportionsofcorndriedbyburningcoalfromflu—orosisendemicareastoestablishc
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