欢迎来到天天文库
浏览记录
ID:55400124
大小:147.78 KB
页数:2页
时间:2020-05-15
《急性心力衰竭患者血浆BNP水平检测及其临床意义探讨.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·22·生堕垫廛Q生!筮!鲞第l3期ChinJModDrugAppl,Jul2015,V。1.9,N。.13急性心力衰竭患者血浆BNP水平检测及其临床意义探讨张桂成刘冠峰杜才杰卢致仁【摘要】目的探讨急性心力衰竭患者血浆B型尿钠肽(BNP)水平检查与临床意义。方法80例急性心力衰竭患者作为观察组,选取同期体检中心80例健康自愿者作为对照组,比较两组血浆BNP、左室射血分数(LVEF)及肺动脉压(PAP),将观察组患者按照纽约心脏病协会(NYHA)分级分为I、Ⅱ、Ⅲ、Ⅳ级,比较不同分级患者血浆BNP水平。结果观察组血浆BNP值明显高于对照组,LvEF和PAP水平明显低于
2、对照组,比较差异有统计学意义(P<0.05);观察组患者随着心功能分级越高血浆BNP水平越高,组间各值比较,差异有统计学意义(尸<0.05)。结论急性心力衰竭患者血浆BNP水平随着心力衰竭程度加重而升高,临床中通过检测患者血浆BNP值判定患者心力衰竭程度。【关键词】急性心力衰竭;B型尿钠肽;检测DOI:10.141646.cnki.cnl1—5581/r.2015.13.011InvestigationofplasmaBNPleveldetectionanditsclinicalsignificanceinacuteheartfailurepatientsZHANG
3、Gui—cheng,LIUGuan-feng,DUCai-jie,eta1.DepartmentofInternalMedicine,GuangdongGuangzhouCityBaiyuaDistrictHospitalofTraditionalChineseMedicine,Guangzhou510470,China【Abstract】objectiveToinvestigateplasmaB—typenatriureticpeptide(BNP)leveldetectionanditsclinicalsignificanceinacuteheanfailure
4、patients.MethodsAtotalof8Oacuteheartfailurepatientsweredividedintoobservationgroup,andanother80healthyvolunteersatthesameperiodwereincontrolgroup.ComparisonsweremadeonplasmaBNP,leftventricularejectionfraction(LVEF),andpulmonaryarterypressure(PAP).ClassificationwasmadebyNewYorkheartasso
5、ciation(NYHA)criterionintoI,II,III,andⅣgrades.PlasmaBNPlevelsineachgradeswerecompared.ResultsTheobservationgrouphadmuchhigherplasmaBNPlevelandlowerLVEFandPAPlevelsthanthecontrolgroup,andtheirdifferenceshadstatisticalsignificance(P6、theincreasingofcardiacfunctionclassification,andthedifferencesacrosseachgrades(P(0.05).ConclusionAcuteheanfailurepatientshavehighplasmaBNPlevelalongwiththeincreasingofheartfailuredegree.DetectionofplasmaBNPlevelcanbeappliedforheartfailurejudgmentinclinic.【Keywords】Acuteheartfailure;B—t7、ypenatriureticpeptide;Detection急性心力衰竭为多种因素作用下心肌病变、心室压力和结合心电图及相关实验室检查明确诊断为急性心力衰竭;②容量增加导致心脏结构和功能明显异常,从而引起心脏排血排除合并有其他严重疾病患者;③排除有严重肝肾功能障碍量急性下降不能满足患者血供的病理状态⋯。BNP具有促患者。进排尿、排钠作用,可舒张血管、拮抗肾素一血管紧张素一l-3方法检测两组患者血清BNP、LVEF及PAP,根据观醛固酮系统收缩血管作用,临床中检测血浆BNP水平可反映察组患者LVEF和左室舒张末期内径(LVEDD)采用NYHA心功能情况J。为探究
6、theincreasingofcardiacfunctionclassification,andthedifferencesacrosseachgrades(P(0.05).ConclusionAcuteheanfailurepatientshavehighplasmaBNPlevelalongwiththeincreasingofheartfailuredegree.DetectionofplasmaBNPlevelcanbeappliedforheartfailurejudgmentinclinic.【Keywords】Acuteheartfailure;B—t
7、ypenatriureticpeptide;Detection急性心力衰竭为多种因素作用下心肌病变、心室压力和结合心电图及相关实验室检查明确诊断为急性心力衰竭;②容量增加导致心脏结构和功能明显异常,从而引起心脏排血排除合并有其他严重疾病患者;③排除有严重肝肾功能障碍量急性下降不能满足患者血供的病理状态⋯。BNP具有促患者。进排尿、排钠作用,可舒张血管、拮抗肾素一血管紧张素一l-3方法检测两组患者血清BNP、LVEF及PAP,根据观醛固酮系统收缩血管作用,临床中检测血浆BNP水平可反映察组患者LVEF和左室舒张末期内径(LVEDD)采用NYHA心功能情况J。为探究
此文档下载收益归作者所有