高通量血液透析在治疗尿毒症患者中的应用.pdf

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1、·24·护理实践与研究2015年第12卷第4期·专科护理·※内科护理高通量血液透析在治疗尿毒症患者中的应用叶爱玲刘君陈惠琳摘要目的：探讨高通量血液透析在治疗尿毒症患者中的应用效果。方法：将120例尿毒症患者随机等分为高通量组和低通量组，高通量组应用高通量血液透析，低通量组应用低通量血液透析。比较两组患者血液透析治疗前后血清肌酐(Scr)、尿素氮(BUN)、血钾(K)、132一微球蛋白(B2一MG)、血清甲状旁腺激素(IPTH)、血红蛋白(Hh)的变化情况。比较两组患者血液透析期间低血压、感染等不

2、良反应的发生率。结果：两组患者在血液透析治疗前后Scr，BUN，K差异无统计学意义(P>0．05)。高通量组在透析治疗后p2一MG，IPTH水平低于低通量组(P0．05)，两组患者耐受性好。结论：采用高通量血液透析治疗尿毒症能有效清除中大分子毒素如p2一MG、IPTH等，减少透析的慢性并发症，改善患者生活质量。关键词尿毒症；高通量血液透析；低通量血液透析；护理doi：10．396

3、9／j．issn．1672—9676．2015．04．011Applicationofhigh—fluxhemodialysistherapyuremiaYEAi—ling，LIUJun，CHENHli—lin(DonggnanPeoplegHospitalofPujiHospital，Dongguan523000)AbstractObjective：Toobservetheclinicalefectsofuremicpatientsbythehigh—fluxhemodialysis．Meth

4、ods：120casesofuremicpatientsadmittedinnephrologyofourhospitalwererandomlydividedintothehJigh～fluxhemodialysisgroupandthelow—fluxhemodialysisgroup．Comparedtheserumcreati-nine，thebloodureanitrogen，andserumpotassium，B2一microglobulinandserumparathyroidho

5、rmonebeforeandafterhemodialysis．Comparedthechangeofhemoglobinandinfectionbeforeandafterhemodialysis．Results：Theserumcreatinine，thebloodureanitrogenandserumpotassiumofthehigh—fluxhe-modialysisgroupwerenotsignificantlydifferent，comparedwiththoseofthelo

6、w—fluxhemodialysisgroupbeforehemodialysis，(P>0．05)．Thep2一micro—globulinlevelsandIPTHinthehigh—fluxhemodialysisgroupweIesignificantlylowerthanthoseinthelow—fluxhemodialysisgroupafterhemodialysis(P<0．051．Thehemoglobinlevelsinthehi．gh—fluxhemodialysisgr

7、oupwassignificantlyhigherthanthoseinthelow—fluxhemodialysisgroupafterhemodi-alysis(P

8、pafterhemodialysis(P>0．05)．Therewaslowincidencerateofadversereactionsinthetwogroups．Conclu—sion：Thehigh—fluxhemodialysistreatmentcanefectivelyremovemacromolecularuremictoxinssuchasB2一microglobulin，IPTH，calleffectivelyreducechroniccomplicationsofhemod