盐酸二甲双胍片联合阿卡波糖胶囊治疗75例2型糖尿病的临床分析.doc

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1、盐酸二甲双胍片联合阿卡波糖胶囊治疗75例2型糖尿病的临床分析　　【摘要】目的评价盐酸二甲双胍片联合阿卡波糖胶囊治疗2型糖尿病的疗效。方法150例2型糖尿病患者，随机分为观察组和对照组，各75例。对照组采用盐酸二甲双胍片治疗，观察组采用盐酸二甲双胍片联合阿卡波糖胶囊治疗。比较两组患者的空腹血糖、餐后2h血糖、糖化血红蛋白、甘油三酯、低密度脂蛋白胆固醇、体质量指数水平。结果治疗后，观察组患者的FBG为mmol/L、2hPG为mmol/L、GHbA1c��%，均低于对照组的mmol/L、mmol/L、%，差异均有统计学意义。治疗后，观察组患者的TG为mmo

2、l/L、LDL-C为mmol/L，均低于对照组的mmol/L、　　mmol/L，差异均有统计学意义。观察组的BMI水平kg/m2和对照组kg/m2比较，差异无统计学意义。结论盐酸二甲双胍片联合阿卡波糖胶囊治疗2型糖尿病的疗效显著，可以达到降低、稳定患者血糖的效果。　　【关键词】盐酸二甲双胍片；阿卡波糖胶囊；2型糖尿病　　DOI：10.14163/j.cnki.11-5547/r.2017.17.061　　Clinicalanalysisofmetforminhydrochloridetabletscombinedwithacarbosecapsule

3、sinthetreatmentof75casesoftype2didabeticmellitusCAOJun-jie，TANGZhao-rong，LUOZhen-yi.DongguanCityDalingshanTownCommunityHealthServiceCenter，Dongguan523820，China　　【Abstract】ObjectiveToevaluatethecurativeeffectofmetforminhydrochloridetabletscombinedwithacarbosecapsulesinthetreatme

4、ntoftype2didabeticmellitus.MethodsAtotalof150type2diabeticmellituspatientswererandomlydividedintoobservationgroupandcontrolgroup，with75casesineachgroup.Thecontrolgroupreceivedmetforminhydrochloridetabletsfortreatment，andtheobservationgroupreceivedmetforminhydrochloridetabletsco

5、mbinedwithacarbosecapsulesfortreatment.Comparisonweremadeonfastingblood-glucose，2hpostprandialglucose，glycosylatedhemoglobin，triglyceride，lowdensitylipoproteincholesterinandbodymassindexlevelintwogroups.ResultsAftertreatment，theobservationgrouphadFBGasmmol/L，2hPGasmmol/L，GHbA1c

6、as%，whichwerealllowerthanmmol/L，mmol/Land%inthecontrolgroup.Theirdifferencehadstatisticalsignificance.Aftertreatment，theobservationgrouphadTGasmmol/L，LDL-Casmmol/L，whichwerealllowerthanmmol/Landmmol/L　　inthecontrolgroup，andtheirdifferencehadstatisticalsignificance.Theobservatio

7、ngrouphadnostatisticallysignificantdifferenceinBMIlevelaskg/m2comparingwithkg/m2inthecontrolgroup.ConclusionCombinationofmetforminhydrochloridetabletsandacarbosecapsulesshowssignificantcurativeeffectandithaseffectofdecreasingandstablingbloodglucose.