国产钆喷酸葡胺联合LAVA动态增强扫描在肝脏病变中的应用-论文.pdf

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1、新医学2013年11月第44卷第11期787I临床研究论著国产钆喷酸葡胺联合LAVA动态增强扫描在肝脏病变中的应用郭宁彭令荣【摘要】目的探讨国产钆喷酸葡胺(Gd．DTPA)联合MRI三维肝脏容积加速采集技术(LAVA)动态增强扫描在肝脏疾病中的应用价值。方法529例肝脏占位性病变患者采用国产Gd—DTPA联合LAVA检测病灶，分析此方法的准确性及强化效果。结果529例经病理学检查确诊肝癌317例、转移瘤107例、血管瘤50例、胆管细胞癌38例、肝脏局灶性结节增生l7例。国产Gd—DTPA联合MRILAVA动态增强扫描检测结果与病理学检查

2、结果的符合率达98。7％(522／529)。正常组织及病变组织出现强化效果者占100％、99．4％。肝癌以显著强化(74．2％)、不均匀强化(73．2％)为主；转移瘤以轻度强化(81．8％)、边缘强化(41．8％)为主；血管瘤以显著强化(76．0％)、边缘强化(46．0％)为主；胆管细胞癌以轻度强化(62．5％)、边缘强化(52．5％)为主；肝局灶性结节增生以显著强化(89．5％)、均匀强化(73．7％)为主。结论国产Gd—DTPA联合MRIIJAVA动态增强扫描对腹部各器官增强效果理想，有助于诊断肝脏病变性质。【关键字】钆喷酸葡胺；L

3、AVA；肝脏疾病DomesticGd-DTPAcombinedwithLAVAdynamiccontrast-enhancedMRIscanningappHcafioninliv-erdiseaseGUONing，PENGLing—rong．DepartmerentofRadiology，theThirdAfiliatedHospitalofSUNYat—senUn&e~ity，Guangzhou510630，China【Abstract】ObjectiveToexploretheapplicationvalueofdomesticga

4、dopentetatedimeglumine(Gd．DTPA)combinedwithliveracquisitionwithvolumeacceleration(LAVA)dynamiccontrast—enhancedMRIscanninginliverdisease．MethodsFivehundredandtwenty—ninepatientsofliverspace·occupyingle—sionreceiveddomesticGd—DTPAcombinedwithLAVAdynamiccontrast．enhancedMR

5、Iscanning．analyzedtheaccuracyofthismethodandstrengtheningeffect．ResultsConfirmedbypathologicalexamination，317casesoflivercancer，107casesofmetastatictumor，50casesofhemangioma，38casesofcholangiocellulareareino—maand17casesofhepaticfocalnodularhyperplasiawerediagnosed．Diagn

6、oseaccordancerateofdomesticGd—DTPAcombinedwithLAVAdynamiccontrast—enhancedMRIscanningwas98．7％．Normanltissueanddis—easedtissueappearstrengtheningeffectaccountedfor100％and99．4％．respectively．LivercancerWasgivenprioritytobesignificantlystrengthened(74．2％)andunevenenhancement

7、(73．2％)；metastatictumorWasgivenprioritytobeslighflystrengthened(81．8％)andedgeenhancement(41．8％)；hemangiomaWasgivenprioritytosignificantlystrengthened(76．0％)andedgeenhancement(46．O％)；eholangiocellulareareino—mawasgivenprioritytobeslightlystrengthened(62．5％)andedgeenhancem

8、ent(52．5％)；hepaticfocalnodularhyperplasiaWasgivenprioritytObeslightlystrengthened(89．5％)andevenenhancem