凉血解毒汤联合心理干预预防银屑病复发的临床研究-论文.pdf

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1、河北中医2014年6月第36卷第6期HebeiJTCM，June2014，Vol36，No．6817凉血解毒汤联合心理干预预防银屑病复发的临床研究刘焕强赵云夕刘娜(河北省中医院皮肤科，河北石家庄050011)【摘要】目的观察凉血解毒汤联合心理干预预防银屑病复发的一临床研究。方法将60例临床痊愈或基本痊愈的银屑病患者随机分成2组，治疗组30例子凉血解毒汤联合心理干预治疗，对照组30例不采用任何干预措施。结果2组复发率比较差异有统计学意义(P<0．05)，治疗组较对照组能明显降低复发率。治疗组治疗后焦虚自评量表(SAS)评分、抑郁自评量表(SDS)评分、皮肤病生活质量指

2、数(DLQI评分)均较对照组治疗后同期降低(P<0．05)。治疗组治疗18个月后躯体化、抑郁、焦虑、敌对、精神病性得分均较本组治疗前改善(P<0．05)，且改善程度优于对照组治疗后同期(P<0．05)。治疗组治疗36个月后除强迫症状得分外，其余症状得分均较本组治疗l8个月后进一步改善(P<0．05)，且改善程度优于对照组治疗后同期(P<0．O5)。结论凉血解毒汤联合心理干预能降低银屑病复发率，明显改善患者的焦虑、抑郁等不良心理状态，提高生活质量。【关键词】银屑病；复发；中药疗法；干预性研究【中图分类号】R758．63；R289．6；R493．25【文献标识码】A【文

3、章编号】11302—2619(2014)06—0817一(13ClinicalstudyofLiangxueJiedudecoctioncombinedwithpsychologicalinterventiononthepreventionofre-currenceofpsoriasis[，Huanqiang，ZHAOYunxi，LIUNa．DepartmentofDermatology，HebeiProvincialHos—pitalofTraditionalChineseMedicine，Hebei，Shijiazhuang050011【Abstract】Obj

4、ectiveToobservetheeffectofLiangxueJiedudecoctioncombinedwithpsychologicalinter-ventiononthepreventionofrecurrenceofpsoriasis．Methods60clinicalrecoveryorfunctionalrecoveriesofpa—tientswithpsoriasiswererandomlydividedintotwogroups．30casesincontrolgroupreceivedwithoutanyinterven—tion．30ca

5、sesintreatmentgroupreceivedLiangxueJiedudecoctioncombinedwithpsychologicalintervention．Re-suitsThedifferencewasstatisticallysignificantontherecurrenceratesoftwogroups(P<0．05)，comparedwiththatofthecontrolgrouptherecurrencerateofthetreatmentgroupcansignificantlyreduced．ThescoresofSAS，SDS

6、andDLQIintreatmentgroupweredecreasedascomparedwiththoseincontrolgroupaftertreatment(尸<0．05)．After18monthsoftreatment，somatization，depression，anxiety，hostility，psychoticscoreintreatmentgroupwereimprovedascomparedwiththosebeforetreatment(P<0．05)．Thedegreeofimprovementintreatmentgroupwass

7、uperiortothatincontrolgroupinthesameperiod(P<0．05)．Exceptobsessive—compulsivesymptomsscore，symptomscoreafter36monthsoftreatmentwereimprovedascomparedwiththoseafter18monthsoftreatment(P<0．05)．Thedegreeofimprovementintreatmentgroupwassuperiortothatincontrolgroupinthesameperiod(P<0．05)．