TACE联合索拉非尼治疗23例中晚期肝细胞肝癌的护理-论文.pdf

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1、介入放射学杂志2014年5月第23卷第5期JlnterventRadiol2014．Vo1．23．No．5——449——·护理论坛Nursingwindow·TACE联合索拉非尼治疗23例中晚期肝细胞肝癌的护理邢桃红，牛焕章，周媛媛，李红杰，杨海燕，李喜娓，汪文翠，詹朦【摘要】目的探讨肝动脉化疗栓塞术(TACE)联合索拉非尼治疗中晚期肝细胞肝癌(HCC)的护理方法。方法选取符合纳入标准的23例中晚期HCC患者，TACE术后3—5d口服甲磺酸索拉非尼。期间观察、记录不良反应和并发症发生情况，出院患者由延续护理小组成员跟踪随访，予以健康教育和相应的护理干预措施。结果所有患者TACE术后

2、均口服索拉非尼进行治疗，联合治疗的不良反应主要是：胃肠道反应(22例)和一过性肝功能损害(23例)。出院患者均得到定期随访和延续护理。结论TACE联合索拉非尼治疗晚期肝细胞肝癌不良反应发生率较高．采用院内观察结合院外延续护理的方式护理此类患者，可减轻治疗期间并发症反应，提高患者的生存质量。【关键词】肝细胞肝癌；索拉非尼；肝动脉灌注化疗栓塞术；护理中图分类号：R735．7文献标志码：A文章编号：1008—794X(2014)一05．0449．03Nursingforpatientswjthadvancedbepatocellularcarcinomareceivingtranscat

3、heterarterialcombinedwithsorafenib：initialexperiencein23casesXINGToo—hong，NIUHuan—zhang，ZHOUYuan·yuan，LIHong-jie，YANGHai—yan，，Xi—wei，WANGWen—cui，ZHANMeng．DepartmentofInterventionalRadiology，theFirstAffiliatedHospita!，HenanUniversityD厂TechnologyandScience，Luoyang，HenanProvince471003，ChinaCorres

4、pondingauthor：NIUHuan—zhang，E—mail：niuhuanzhang@126．com【Abstract】ObjectiveTodiscussthenursingcareforpatientswithadvancedhepatocellularcarcinoma(HCC)whoarereceivingtranscatheterarterialchemoembolization(TACE)combinedwithsorafenib．MethodsAtotalof23consecutivepatientswithadvancedHCCwhomettheinclu

5、sioncriteriawereenrolledinthisstudy．TACEwascardedoutinallpatients．Three—fivedaysafterTACEthepatientsstartedtoorallytakesorafenib．Duringthetreatmentcourse，thepatientswerekeptundercloseobservationforadversereactionsandcomplications．Afterleavingthehospitalthepatientswerefollowedupbytheextendedcar

6、eteammembers，andhealtheducationaswellasappropriatenursinginterventionwascarriedout．ResultsAllpatientswithadvancedHCCtooksorafeniborallyafterTACE．Themajoradverseeventsandcomplicationsweregastrointestinaladversereactions(n=22)andtransientliverdysfunction(n=23)．Afterleavingthehospitalallthepatien

7、tsreceivedregularfollow-upexaminationandextendednursingcare．ConclusionUsually，theincidenceofadversereactionsishigherinpatientswithadvancedHCCafterTACEcombinedwithsorafenibtreatment．Carefulin—hospitalobservationandextendedout—hospitalnur