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时间:2020-05-07
《内镜套扎联合硬化剂夹心法治疗食管静脉曲张破裂出血的远期疗效观察-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、第26卷第1期第1页临床消化病杂志Vo126No1P12014年2月ChinJClinGastroentero1Feb2014·论著·doi:10.3870/lcxh.j.issn.1005—541X.2014.01.01内镜套扎联合硬化剂夹心法治疗食管静脉曲张破裂出血的远期疗效观察杨文涛,张军,于红刚△(武汉大学人民医院消化内科,湖北武汉430060)摘要:[目的]探讨内镜下静脉曲张套扎同时应用硬化剂夹心法(套扎一硬化一套扎即EVL-EVS-EVI)治疗食管静脉曲张破裂出血的疗效。[方法]对23例肝硬化食管静脉曲张破裂出血的患者采用夹心法治疗,每
2、条曲张静脉结扎皮圈不超过3个,并在2个结扎点之间的曲张静脉内注射l~3ml硬化剂。其中lo例在首次内镜治疗时接受食管静脉造影检查。于治疗后2周、i个月、3个月、6个月、12个月胃镜随访,了解静脉曲张变化情况,记录患者不良反应及并发症。[结果]1o例行静脉造影检查中7例硬化剂在曲张静脉内滞留时间超过40min。夹心法控制活动性食管静脉曲张出血的止血成功率为100,静脉曲张消除率为86.9%(20/23),再出血发生率为8.6(2/23),随访期内静脉曲张复发率为13.0(3/23)。[结论]夹心法能使硬化剂在曲张静脉内滞留较长时间,在一次治疗后能有效
3、提高静脉曲张消除率,降低再出血率及静脉曲张复发率,是内镜下治疗食管静脉曲张破裂出血的较理想选择。关键词:肝硬化;食管静脉曲张;内镜治疗;夹心法中图分类号:R575.2文献标志码:A文章编号:1005—541X(2014)01—001—03Endoscopicvariceallitionjointhardenersandwichmethodlong-termefficacyofthetreatmentofesophagealvaricesYANGWen—tao,ZHANq3UNUHong—gang△(DepartmentofGastroenterol
4、ogy,RenminHospital,WuhanUniversity,Wuhan430060,China)△Correspondingauthor,E—mail:honggangyu@sohu.comAbstract:LObjective]toexploretheendoscopicvaricealligationefficacyofapplicationsclerotherapymethod(1igation—hardening—ligation)treatmentofesophagealvarices.[-Methods]Twenty-thre
5、epatientswithcirrhosisandesophagealvaricesbleedinginpatientswithsandwichmethod(EVL-EVS-EVL)combi—nationtherapy,eachvaricoseveinsbalanceZappicircleofnotmorethanthree,andvaricoseveinsbetweenthetwoligationpointsinjected1to3mlofhardeningagent.Ofwhich10wereacceptedinthefirstendo—sc
6、opictreatmentofesophagealvenography.Recordsofpatientswithadversereactionsandcomplicationsaf—tertreatmentfortwoweeksinone,three,sixandtwelvemonthsendoscopicfollowforvaricoseveinschange.[Results]Tenroutinevenographyinsevencaseshardenerresidencetimeinthevaricoseveinover40minutes.
7、Thesandwichmethodtocontroltheactivityofesophagealvarieealbleeding(EVB)hemostaticsuccessrateof100,andvaricealobliterationratewas86.9(20/23),rebleedingratewas8.6(2/23),thefollow-upperiod,theintravenousvaricoserecurrenceratewas13.0H(3/23).[Conclusion]Thesand—wichmethodhardenercan
8、remaininthevaricoseveinlongtime,afterthefirsttreatmentcaneffe
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