天麻钩藤饮加减方联合硝苯地平缓释片治疗高血压临床疗效观察-论文.pdf

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1、世界中西医结合杂志2014年第9卷第5期WorldJournalofIntegratedTraditionalandWesternMedicine2014，Vo1．9，No．5·517··临床研究·天麻钩藤饮加减方联合硝苯地平缓释片治疗高血压临床疗效观察穆善生潘贵超【摘要】目的观察天麻钩藤饮加减方联合硝苯地平缓释片治疗高血压的临床疗效。方法75例高血压患者经中医辨证均为肝阳上亢型，随机分为治疗组38例和对照组37例。两组均给予硝苯地平缓释片，每次20mg，2次·d一。治疗组同时给予天麻钩藤饮加减方，水煎服，1剂·d～。两组均治疗8周，8周后观察疗效。结果治疗

2、组总有效率为94．7％(36／38)，明显高于对照组总有效率83．8％(31／37)(P<0．05)；治疗后治疗组收缩压和舒张压分别为(129．8±4．3)mmHg和(84．9±4．7)mEHg，较治疗前明显降低(P<0．05)；治疗后对照组收缩压和舒张压与治疗前比较虽下降但差异无统计学意义(P>0．05)。结论天麻钩藤饮加减方联合硝苯地平缓释片治疗肝阳上亢型高血压，降压效果明显，能显著改善高血压引起的相关症状，安全性高，适合临床推广。【关键词】高血压；肝阳上亢；天麻钩藤饮加减方；硝苯地平缓释片【中图分类号】R544．1【文献标识码】A【文章编号】1673—

3、6613(2014)05—0517—03ClinicalEficacyonHypertensionTreatedwithModifiedTianmaGoutengDecoctionandSustainedReleaseNifedipineTabletsMUShan—sheng，PANGui～chao(BeijingChangpingDistrictIntegratedChineseandWesternMedicineHospital，Beijing102208)【Abstract】ObjectiveToobservetheclinicaleficacyonh

4、ypertensiontreatedwithmodifiedTianmaGoutengDecoctionandSustainedReleasedNifedipineTablets．MethodsSeventy—fivecasesofhyperten—sionweredifferentiatedashyperactivityofliveryangintraditionalChinesemedicineandwererandomizedin—toatreatmentgroup(38cases)andacontrolgroup(37cases)．TheSustai

5、nedReleasedNifedipineTabletswereprescribedinthetwogroups，20mgeachtime，twiceaday．Inthetreatment，themodifiedTianmaGout—engDecoctionwasprescribedfororaladministration，onedoseaday．Thetreatmentlastedfor8weeksinthetwogroups．Theeficacywasobservedin8weeks．ResultsThetotaleffectiveratewas94．

6、7％(36／38)，whichwashigherapparentlythan83．8％(31／37)inthecontrolgroup．Mtertreatment，thesystolicpressureanddiastolicpressurewere(129．8±4．3)mlTlHgand(84．9±4．7)mmHg，whichwerelowerapparentlythanthosebeforetreatment(P<0．05)．Aftertreatment．thesystolicpressureanddiastolicpressurewerere—duce

7、d．butthedifferenceswerenotsignificantascomparedthosebeforetreatmentinthecontrolgroup(P>0．05)．ConclusionThecombinedmedicationofthemodifiedTianmaGoutengDecoctionandSustainedRe—leasedNifedipineTabletsachievestheremarkableeffectsonhypertensiondifferentiatedashyperactivityofliveryang．It

8、relievessignificantlythere