低分子肝素治疗妊娠晚期羊水过少疗效观察-论文.pdf

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1、《中国医学创新》第1o卷第33期(总第279期)2013年11月临扇与实践Linchuangyushan低分子肝素治疗妊娠晚期羊水过少疗效观察李传棠①周扬①王继昌①【摘要】目的：探讨低分子肝素治疗妊娠晚期羊水过少的疗效。方法：将62例妊娠晚期羊水过少孕妇随机分为治疗组和对照组，每组31例，两组孕妇常规治疗相同，治疗组加低分子肝素治疗，所有孕妇于治疗前、治疗结束后次日晨分别采血检测血液高凝状态指标变化(D一二聚体及FIB)、以多普勒超声检测羊水指数(AFIo结果：两组治疗后D一二聚体及FIB均明显下降(P<0．01)，且治疗组较对照组下降明显

2、(P

3、onofChina。2013，10(33)：029-031【Abstract】0bjecfive：Toinvestigatethelowmolecularweightheparinoligohydramniosefficacyinthethirdtrimesterofpregnancy．Method：62casesoflatepregnancyoligohydramniospregnantwomenwererandomlydividedintotreatmentgroupandcontrolgroup，31casesineachgroup，

4、twogroupsofpregnantwomenthesameastheconventionaltreatment，thetreatmentgroupandthelowmolecularweighthepafin，allpregnantwomenpriortotreatment。endoftreatmentnextmorningbloodsampleswerecollectedto~letectthehypercoagulablestatesindicators(D—dimerandFIB)，Dopplerultrasoundamnioti

5、efluidindex(AFI)．Result：AftertwotreatmenttheD-dimerandFIBsignificantlydecreased(P<0．01)；treatmentgroupthanthecontrolgroupdecreasedsignificantly(P<0．05)；AFIvalueinthetwogroupsaftertreatmentweresignificantlyincreased(P<0．01)，whilethetreatmentgroupwassignificantlyhigherthanth

6、atinthecontrolgroup(P<0．05)．Conclusion：ThelowmolecularweightheparinCallimprovethethirdtrimesterofpregnancyamnioticfluidlessbloodofpregnantwomenhypercoagulablestateindicatorsandamnioticfluidindex，anticoagulant，theroleofmicrocirculation，curativeefectisdistinct．【Keywords】Olig

7、ohydramnios；Lowmolecularweightheparin；Pregnancyoutcomes；TreatmenteffectFirst-author’Saddress：BojiAf'fliatedHospitalofSunYat-senUniversity。Zengeheng511300。Chinadoi：10．3969~．issn．1674—4985．2013．33．014羊水过少可以发生在妊娠各期，早中期羊水过少多因胎妊娠期并发症及内外科疾病。随机分为治疗组与对照组，每儿畸形所致，往往以流产告终。临床上以晚期妊娠(28

8、周后)组31例。两组孕妇平均年龄、孕周、孕产次、孕龄比较差多见Il】。妊娠晚期羊水量少于300mL者称羊水过少。目前，异均无统计学意义(P>0．05)，见表1。羊水过少原因不明，