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《AFP异质体阳性肝细胞癌的超声、超声造影特点分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、全科医学2014年6月第12卷第6期ChineseJournalofGeneralPractice,June2014,Vo1.12,No.6·891··全科医学论著·AFP异质体阳性肝细胞癌的超声、超声造影特点分析袁华琴,王晓嫒摘要:目的探讨AFP异质体阳性(AFP—L3/AFP≥10%)肝癌的超声及超声造影特点,为AFP异质体阳性肝癌患者预后差提供超声影像学依据。方法随机选择AFP异质体阳性肝癌57例(阳性组)和AFP异质体阴性肝癌30例(阴性组),对比分析2组的超声及超声造影表现,并行统计学分析。结果阳性组病灶最大径1>5cm41例(71.9%),多发或弥漫阳性组34例(59.6%
2、),边缘不清或不规则阳性组39例(68.4%),回声不均匀阳性组43例(75.4%),侵犯血管及肝内转移阳性组为31例(56.1%),均显著高于阴性组(P<0.05);病灶呈高回声30例(52.6%),高于阴性组10例(33.3%),而低回声12例(21.1%),低于阴性组l2例(40.0%),但2组无统计学差异(P>0.05)。超声造影:阳性组23例表现为“快进快出”16例(69.6%),“快进慢出”7例(30.4%);而阴性组15例表现为“快进快出”5例(33.3%),“快进慢出”10例(66.7%),2组差异具有统计学意义(P<0.05)。结论AFP异质体阳性肝癌超声检查具有肿瘤
3、体积大、浸润性生长、易侵犯血管和发生肝内转移,增强以“快进快出”为主的影像学特点,提示预后不良。关键词:肝细胞肝癌;甲胎蛋白异质体;二维灰阶超声;超声造影中图分类号:R445.1R735.7文献标识码:A文章编号:1674-4152(2014J06-0891-03Imagingfeaturesofultrasoundandcontrast-enhancedultrasoundinhepatocellularcarcinomawithdiferentAFPvariantYUANHua—qin,WANGXiao—man.DepartmentofUltrasound,theAfiliated
4、HospitalofHangzhouNormalUniver-sity,Hangzhou310015,Zhejiang,ChinaAbstract:ObjectiveToinvestigatetheimagingfeaturesofuhrasoundandcontrast-enhancedultrasoundofhepatocellu-·larcarcinoma(HCC)withapositiveAFP—L3.MethodsTheAFP—L3positiveHCC(n=57)(positivegroup)andtheAFP—L3negativeHCC(n=30)(negativegro
5、up)wererandomlyselected,theimagingfindingsofultrasoundandcontrast—enhancedultrasoundwerecomparativelyanalyzedinthetwogroupsbystatistics.ResultsInthepositivegroup,41cases(71.9%)≥5cminthelesionsmaximumdiameter,34cases(59.6%)inthemuhipleordiffuse,39cases(68.4%)intheunclearorirregularedge,43cases(75
6、.4%)intheunevenecho,22cases(38.6%)intheinvadebloodvesselsand11cases(19.3%)intrahepaticmetastasisinthepositivegroup,markedhigherthanthatofthenegativegroup(P<0.05).But30cases(52.6%)and12cases(21.1%)inthelesions’highandlowecho,thetwogroupswerenosignifi·cantdifference(P>0.05).“Quicklyinandquicklyout
7、”in16cases(69.6%)and“quicklyinandslowout”in7eases(30.4%)wereshowedincontrast—enhanceduhrasoundof23casesinthepositivegroup,whichweredifferencecomparedwiththenegativegroup(P<0.05).ConclusionTheAFP—L3positiveHCChasthepoorprogno
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