中西药联用治疗原发性骨质疏松症效果分析.pdf

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1、·2438·现代医药卫生2014年8月30日第30卷第l6期JModMedHealth，August30，2014，Vo1．30，No．16·短篇论著·中西药联用治疗原发性骨质疏松症效果分析霍钻云，朱干，吴声振(佛山市中医院制剂中心，广东佛山528000)【摘要】目的分析骨宝I：／服液联合鲑鱼降钙素注射液(密盖息注射液)对原发性骨质疏松症的治疗效果。方法将2010年9月至2012年9月120例原发性骨质疏松症患者分为治疗组和对照组，各60例。治疗组给予骨宝口服液和密盖息注射液联合治疗，对照组给予密盖息注射液治疗，疗程

2、均为3个月．观察比较两组患者骨密度的变化和临床疗效。结果治疗组，临床总有效率[95．O％(57／60)】高于对照组[83．3％(50／60)]，差异有统计学意义(P<0．05)；两组治疗后骨密度值均有所升高，治疗组优于对照组。差异有统计学意义(P

3、5519I2014)162438—02TherapeuticanalysisofintegratedtreatmentofChineseandWesternmedicineinthetreatmentofprimaryosteoporosisHuoZuanyun，ZhuGan，WuShengrhen(CenterforPreparations，FoshanHospitalofTCM，Foshan，Gua~gdong528000，China)【Abstract1ObjectiveToanalyzethetherapeu

4、ticeffectsofbonetreasureoralliquidcombinedwithsalmoncalcitoninseecalcimarinjection(Miacalcicinjection)intreatingprimaryosteoporosis．MethodsAtotalof120patientswithprimryosteo—porosis，whowerehospitalizedinFoshanHospitalofTCMfromSeptember2010toSeptember2012，weredi

5、videdintotreatmentgroupandcontrolgroup，60casesineachgroup．ThetreatmentgroupwastreatedwithbonetreasureoralliquidcombinedwithMi—acalcicinjection，whilethecontrolgroupwastreatedwithMiaealcicinjection．Thetreatmentcourseinbothgroupswas3months．Theclinicaleffectandchan

6、gesofbonemineraldensity(BMD)ofpatientsinbothgroupswei'eobserved．ResultsThetotalefec—tiveratewas95．0％(57／60)inthetreatmentgroup，whichwasnothigherthanthatinthecontrolgroup83．3％(50／60)，thedifferencebetweenthetwogroupshadstatisticalsignificance(P<0．05)．BMDincreased

7、inbothgroups，butthetreatmentgroupwashigherthanthecontrolgroupwithstatisticallysignificantdifference(P<0．05)．ConclusionBonetreasureoralliquidcombinedwithMiacalcicinjectionhasgoodtherapeuticefectsforprimaryosteoporosiswithlittleadversereaction，anditiswo~hyapplica

8、—tionasclinicalreference．【Keywords】Osteoporosis；Bonedensity；Caleitonin；Salmonidae；Bonetreasureoralliquid骨质疏松症是一种全身性骨骼疾病，以骨量减少、骨组织结痛、腰膝酸软等临床症状，将患者分为两组。治疗组60例，其中男构发生退化、骨强度降低、脆