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《不同麻醉方式对肝癌切除患者术后感染影响的研究.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·4566·中华医院感染学杂志2014年第24卷第18期ChinJNosocomiolVo1.24No.182014doi:10.11816/cn.ni.2014—134017·论著·不同麻醉方式对肝癌切除患者术后感染影响的研究赵延涛,冯仙菊,王静,包剑锋(1.杭州市西溪医院麻醉科3.放射科4.科教科,浙江杭州310023;2.台州医院消化内镜中心,浙江台州317000)摘要:目的探讨不同麻醉方式对肝硬化肝癌切除患者术后感染的影响,以期提高对肝癌患者手术麻醉方法的认识,提高治疗水平。方法选取2006年2月~2013年6月在医院进行肝硬化肝癌切除患者186例,依据麻醉方法分为
2、3组,硬膜外组6O例,采用单纯连续硬膜外麻醉,全麻组62例,采用静脉给药全身麻醉,联合组64例,采用连续硬膜外联合全身麻醉方法,对比3组患者的麻醉效果及术后感染情况。结果联合组患者术中体温、失血量、尿量、术后30rain谷丙转氨酶(ALT)、术后30min谷草转氨酶(AST)、心率均显著优于硬膜外组、全麻组,硬膜外组优于全麻组患者,差异有统计学意义(P<0.05);联合组术后呼吸道感染、手术切口感染率、术后排气时间、术后寒颤、恶心、呕吐、患者满意度、苏醒时间显著优于硬膜外组、全麻组患者,硬膜外组患者优于全麻组,差异有统计学意义(P3、生因麻醉操作或麻醉用药导致的严重不良反应发生。结论采用连续硬膜外联合全身麻醉方法可明显降低对术中各项生命体征的影响、有效维护基础体温、减轻对患者机体免疫系统及肝功能的影响,降低术后感染的发生,麻醉效果较好,为肝硬化肝癌切除最佳麻醉方法。关键词:肝硬化肝癌;麻醉方式;硬膜外麻醉;全身麻醉中图分类号:R619。。.3文献标识码:A文章编号:1005—4529(2014)18-4566—03Influenceofdifferentanesthesiaapproachesonpostoperativeinfectionsinlivercancerresectionpatients一4、、ZHAOYan—tao,FENGXian—Ju,WANGJing,BAOJian—feng(*HangzhouXixiHospital,Hangzhou,Zejiang310023,China)Abstract:OBJECTIVEToexploretheimpactofdifferentanesthesiaapproachesonpostoperativeinfectionsinpa—tientsundergoingcirrhosisandlivercancerresectionsoasimprovetheawarenessofanesthesiaandraisethel5、eveloftreatment.METHODSAtotalof186patientswhounderwentthecirrhosisandlivercancerresectioninthehos—pitalfromFeb2006toJun2013wereenrolledinthestudyanddividedintothethreegroupsaccordingtothearies—thesiaapproaches;theepiduralgroupwith60patientswastreatedwithsinglecontinuousepiduralanesthesia,t6、hegeneralanesthesiagroupwith62patientswastreatedwithintravenousadministrationforgeneralanesthesia,andthecombinationgroupwith64patientswasgiventhecontinuousepiduralanesthesiacombinedwithgeneralanes—thesia;theeffectofanesthesiaandtheincidenceofpostoperativeinfectionswereobservedandcomparedam7、ongthethreegroups.RESULTSTheintraoperativebodytemperature,bloodlossvolume,urinevolume,alanineamin—otransferase30minaftersurgery,aspartateaminotransferase30minaftersurgery,andheartrateofthecombina—tiongroupweresignificantlybetterthanfhoseoftheepiduralgroupandth
3、生因麻醉操作或麻醉用药导致的严重不良反应发生。结论采用连续硬膜外联合全身麻醉方法可明显降低对术中各项生命体征的影响、有效维护基础体温、减轻对患者机体免疫系统及肝功能的影响,降低术后感染的发生,麻醉效果较好,为肝硬化肝癌切除最佳麻醉方法。关键词:肝硬化肝癌;麻醉方式;硬膜外麻醉;全身麻醉中图分类号:R619。。.3文献标识码:A文章编号:1005—4529(2014)18-4566—03Influenceofdifferentanesthesiaapproachesonpostoperativeinfectionsinlivercancerresectionpatients一
4、、ZHAOYan—tao,FENGXian—Ju,WANGJing,BAOJian—feng(*HangzhouXixiHospital,Hangzhou,Zejiang310023,China)Abstract:OBJECTIVEToexploretheimpactofdifferentanesthesiaapproachesonpostoperativeinfectionsinpa—tientsundergoingcirrhosisandlivercancerresectionsoasimprovetheawarenessofanesthesiaandraisethel
5、eveloftreatment.METHODSAtotalof186patientswhounderwentthecirrhosisandlivercancerresectioninthehos—pitalfromFeb2006toJun2013wereenrolledinthestudyanddividedintothethreegroupsaccordingtothearies—thesiaapproaches;theepiduralgroupwith60patientswastreatedwithsinglecontinuousepiduralanesthesia,t
6、hegeneralanesthesiagroupwith62patientswastreatedwithintravenousadministrationforgeneralanesthesia,andthecombinationgroupwith64patientswasgiventhecontinuousepiduralanesthesiacombinedwithgeneralanes—thesia;theeffectofanesthesiaandtheincidenceofpostoperativeinfectionswereobservedandcomparedam
7、ongthethreegroups.RESULTSTheintraoperativebodytemperature,bloodlossvolume,urinevolume,alanineamin—otransferase30minaftersurgery,aspartateaminotransferase30minaftersurgery,andheartrateofthecombina—tiongroupweresignificantlybetterthanfhoseoftheepiduralgroupandth
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