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时间:2020-05-02
《不同麻醉方式对老年患者术后认知能力的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、职业与健康2013年9月第29卷第17期OecupandHealth,Sept.2013,Vo1.29,No.17·2189··流行病学与预防保健·不同麻醉方式对老年患者术后认知能力的影响InfluenceofdifferentanesthesiamethodsOilpostoperativecognitiveabilityofelderlypatients胡红侠,王熙,李筠HUHong—xia,WANGXi,LIYun陕西省宝鸡市第二人民医院,721000摘要:目的通过简易智能状态检查法(MMSE),调查3种不同麻醉方法对老年患者术后早期认知功能的影响。方法将
2、285例老年手术患者随机分为全身麻醉复合硬脊膜外阻滞组(GEA组)、单纯全身麻醉组(GA组)和硬膜外麻醉组(EID组),每组各95例。分别在术前及术后12、24、72h、第7天和1个月,对患者采用MMSE进行神经、精神功能评定。结果术后认知障碍(POCD)主要发生在术后24h内,术后第7天除GA组有2例POCD外,其余均恢复正常;GA组出现POCD的比例最大、最为严重,GEA组次之,3组之问差异有统计学意义(P<0.05);术后1月POCD患者均恢复正常。结论硬膜外麻醉、单纯全身麻醉和全身麻醉复合硬脊膜外阻滞均与老年患者手术后认知功能障碍的发生有关;全身麻醉对认
3、知功能的影响最大,而硬膜外麻醉的影响最小;术后认知障碍持续的时间相对较短,恢复良好。关键词:认知功能障碍;全身麻醉复合硬脊膜外阻滞;单纯全身麻醉;硬膜外麻醉中国图书资料分类号:R614文献标识码:B文章编号:1004—1257I2013)17—2189—03InfluenceofdiferentanesthesiamethodsonpostoperativecognitiveabilityofelderlypatientsHUHong-xia,WANGXi,LIYunTheSecondPeople'sHospitalofBaliCity,Shaanxi,7210
4、00,ChinaAbstract:[Objective]ByMini—MentalStateExamination(MMSE),toinvestigatetheinfluenceofthreedifferentanestheticmethodsonearlypostoperativecognitivefunctioninelderlypatients.[Methods]285casesofelderlysurgicalpatientswererandomlydividedintothegeneralanesthesiacombinedwithepiduralan
5、esthesiagroup(GEAgroup),generalanesthesia(GAgroup)andepiduralanesthesiagroup(EIDgroup),95casesineachgroup.ThenervesfunctionandmentalfunctionwereassessedbyMMSEbeforeoperationand12hoursI24hours,72hours,7daysandonemonthafteroperation.[Results]Thepostoperativecognitivedysfunction(POCD)oc
6、curredwithin24hoursafteroperation-therewereonly2casesofPOCDinGAgroup7daysafteroperation,andrestpatientswerereturnedtonorma1.TheproportionofPOCDinGAgroupwasthehighest,whilethePOCDwasthemostseri—ous,followedbyGEAgroup,andthedifferencesbetweenthethreegroupswerestatisticallysignificant(P
7、<0.05).AllpatientswithPOCDwerebacktonormalonemonthafteroperation.[Conclusion】Theepiduralanesthesia,generalanesthesiaandgeneralanesthesiacombinedwithepiduralanesthesiaarerelatedtotheocCH1Tenceofcognitivedysfunctioninelderlypatientsaftersurgery.Thegeneralanesthesiahasthegreatesteffecto
8、ncognitivefu
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