hiv_aids患者浅表淋巴结肿_省略__4_t淋巴细胞计数的相关性分析_蔡琳

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1、临床肺科杂志2013年10月第18卷第10期1837+HIV/AIDS患者浅表淋巴结肿大与其CDT淋巴细胞计数的相关性分析4蔡琳朱迎春何盛华周锐峰王燕岳冀+【摘要】目的探讨HIV/AIDS患者肿大浅表淋巴结的病理改变与其CD4T淋巴细胞计数的相关性。方法对81例++HIV/AIDS患者肿大的浅表淋巴结组织进行病理学检查，并检测其外周血CD4T淋巴细胞计数。结果CD4T淋巴细胞＜100cells/ul有58例，100～200cells/ul有17例，＞200cells/ul有6例。主要病理改变结核病48例，艾滋病相关淋巴结病15例，淋+巴结反应性增

2、生14例。合并浅表淋巴结肿大的结核病患者的CD4T淋巴细胞计数比较差异有统计学意义(P=0.008)。合并++淋巴结反应性增生患者的CD4T淋巴细胞计数比较差异有统计学意义(P=0.018)。结论检测外周血CD4T淋巴细胞计数对出现浅表淋巴结肿大的HIV/AIDS患者的临床诊断具有重要的参考价值。+【关键词】人类免疫缺陷病毒;获得性免疫缺陷综合征;淋巴结;CD4T淋巴细胞;结核+ＲelationshipbetweensuperficiallymphadenectasisandCD4T-lymphocytecountsinHIV/AIDSpatie

3、ntsCAILin，ZHUYing-chun，HESheng-hua，ZHOUＲui-feng，WANGYan，YUEJiInfectiousDiseasehospitalofChengdu，Chengdu，Sichuan610061，China+【Abstract】ObjectiveToinvestigatethecorrelationbetweenpathologicalchangesoflymphnodesandCD4T-lymphocytecountsandsuperficiallymphadenectasisinHIV/AIDSpati

4、ents．Methods81HIV/AIDSpatientswithsuperficiallymphadenectasisweregiven++lymphnodebiopsyandacceptedperipheralbloodCD4T-lymphocytecountdetection．ＲesultsTherewere58patientswithCD4T-lym-+phocytecountslowerthan100cells/μl，17patientswithCD4T-lymphocytecountsbetween100cells/μland200

5、cells/μland6patients+withCD4T-lymphocytecountsmorethan200cells/μl．Thepathologicalresultsincluded40casesoftuberculosis，9casesofAIDS-related+lymphadenopathyand14casesofreactivehyperplasia．TherewasstatisticaldifferenceoftheCD4T-lymphocytecountsinHIV/AIDSpa-tientswithtuberculosis

6、(Fisher，P=0.008)．ConclusionThemajorcauseofsuperficiallymphadenopathyinHIV/AIDSpatientsisin-+fection，andthemostcommoncauseistuberculosis．ThelowertheCD4T-lymphocytecounts，thegreatertheriskoftuberculosisis．The+detectionofCD4T-lymphocytecountinperipheralbloodmightbeusefulforclini

7、caldiagnosisinHIV/AIDSpatientswithsuperficiallymphadenectasis．+【Keywords】HIV;AIDS;lymphnode;CD4T-lymphocyte;tuberculosis艾滋病(acquiredimmunedeficiencysyndrome，AIDS)是由doi:10．3969/j．issn．1009－6663．2013．10．044人类免疫缺陷病毒(humanimmunodeficiencyvirus，HIV)引起基金项目:四川省卫生厅科研课题(No2010－100062)

8、的以特异性细胞免疫功能受损为主要特点的全身性疾病。由作者单位:610061四川成都，成都市传染病医院+于HIV的感染，导致CD4T淋巴细