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时间:2020-04-24
《化疗对恶性肿瘤患者糖化血红蛋白和空腹血糖的影响-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、检验医学与临床2014年4月第11卷第8期LabMedClin,April2014,Vo1.11,No.8·1025··论著·化疗对恶性肿瘤患者糖化血红蛋白和空腹血糖的影响罗阔(重庆市中山医院肿瘤科400013)【摘要】目的分析化疗对恶性肿瘤患者糖化血红蛋白和空腹血糖的影响。方法选取重庆市中山医院2011年4月至2013年4月收治的5O例恶性肿瘤患者,其中7例有糖尿病病史,对化疗前、首次化疗后的空腹血糖、血红蛋白变化进行分析。结果对无糖尿病患者进行化疗后,22例出现高血糖(51.2),¨例出现糖化血红蛋白升高(25.6),10例患者确诊为糖尿病(23.
2、3)。对糖尿病患者进行化疗后,6例出现高血糖、糖化血红蛋白升高。糖尿病患者、无糖尿病患者首次化疗后,糖化血红蛋白水平均明显高于化疗前,化疗前后对比差异有统计学意义(P<0.05)。无糖尿病患者2、7、8次化疗前,糖化血红蛋白水平明显高于化疗前,4次化疗前,空腹血糖水平明显高于化疗前,化疗前后差异有统计学意义(P3、4.08.008文献标志码:A文章编号:1672-9455(2014)08—1025—03EffectsofchemotherapyonglycatedhemoglobinandfastingplasmaglucoseinpatientswithmalignanttumorLUOKuo(OncologyDepartment,ZhongshanHospitalofChongqingCity,Chongqing400013)、[Abstract]ObjectiveToexploretheeffectofchemotherapyonglycatedhemog4、lobinandfastingplasmaglu—coseinpatientswithmalignanttumors.MethodsAtotalof50patientswithmalignanttumor,treatedinthishospitalbetweenJanuary2010andDecember2011,wereenrolled,including7patientswithpreviouslydiagnoseddiabetesbe—forechemotherapy.Fastingplasmaglucoseandglycatedhemoglob5、inweredetectedbeforeandafterthefirsttimeofchemotherapy.ResultsAfterchemotherapytreatment,among43patientswithoutpreviouslydiagnoseddiabetes,22patients(51.1)werewithelevatedfastingplasmaglucoselevel,11cases(25.6)werewithelevatedglycatedhe—moglobinand10cases(23.3)werediagnosedasdia6、betes.Afterchemotherapytreatment,among7patientswithpreviouslydiagnoseddiabetes,6caseswerewithbothelevatedfastingplasmaglucoseandglycatedhemoglobinleve1.Afterthefirsttimeofchemotherapy,levelsofglycatedhemoglobininpatientswithorwithoutpreviouslydiagnoseddiabeteswerebothhigherthanl7、evelsdetectedbeforechemotherapy(P8、ourthcycle。wereevidentlyhigherthanthosedetected
3、4.08.008文献标志码:A文章编号:1672-9455(2014)08—1025—03EffectsofchemotherapyonglycatedhemoglobinandfastingplasmaglucoseinpatientswithmalignanttumorLUOKuo(OncologyDepartment,ZhongshanHospitalofChongqingCity,Chongqing400013)、[Abstract]ObjectiveToexploretheeffectofchemotherapyonglycatedhemog
4、lobinandfastingplasmaglu—coseinpatientswithmalignanttumors.MethodsAtotalof50patientswithmalignanttumor,treatedinthishospitalbetweenJanuary2010andDecember2011,wereenrolled,including7patientswithpreviouslydiagnoseddiabetesbe—forechemotherapy.Fastingplasmaglucoseandglycatedhemoglob
5、inweredetectedbeforeandafterthefirsttimeofchemotherapy.ResultsAfterchemotherapytreatment,among43patientswithoutpreviouslydiagnoseddiabetes,22patients(51.1)werewithelevatedfastingplasmaglucoselevel,11cases(25.6)werewithelevatedglycatedhe—moglobinand10cases(23.3)werediagnosedasdia
6、betes.Afterchemotherapytreatment,among7patientswithpreviouslydiagnoseddiabetes,6caseswerewithbothelevatedfastingplasmaglucoseandglycatedhemoglobinleve1.Afterthefirsttimeofchemotherapy,levelsofglycatedhemoglobininpatientswithorwithoutpreviouslydiagnoseddiabeteswerebothhigherthanl
7、evelsdetectedbeforechemotherapy(P8、ourthcycle。wereevidentlyhigherthanthosedetected
8、ourthcycle。wereevidentlyhigherthanthosedetected
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