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时间:2020-04-24
《丁苯酞治疗急性脑梗死患者疗效及血管内皮生长因子血清水平变化-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、髓矗珥学杂志,2014,24(3):35—37◎2014CHINESEJOURNALOFMICROCIRCULATIONdoi:10.3969/j.issn.1005—1740.2014.03.012丁苯酞治疗急性脑梗死患者疗效及血管内皮生长因子血清水平变化易建魏娟*艾池波倪志林[中图分类号]R465.3[文献标识码]A[文章编号]1005—1740(2014)03—0035—03目的:观察丁苯酞对急性脑梗死的临床疗效及患者血清血管内皮生长因子(VEGF)水平变化方法:68例急性脑梗死患者,简单随机化分组法分为观察组(一35)和对照组(n一33)。对照组给予口服阿斯匹林片、依达拉奉针静
2、滴;观察组在对照组基础上加服丁苯酞软胶囊。两组疗程均为14天。比较两组临床疗效以及治疗前和治疗14天后神经功能缺损程度(NIHss)和血清VEGF水平。结果:观察组治疗后临床总有效率高于对照组(P3、nfarctionandtheChangesofVascularEn-dothelialGrowthFactorSerumLevelsYIJiang,WEIJuan一,AIChibo,NIZhilinTheNinthHospitalofWuhanCity,Wuhan430060,China;RenminHospitalfoYunyangCountryofChongqingCity,Yunyang404500,China;Correspondingauthorobjective:Toobservetheclinicaltherapeuticeffectandserumvarcularen4、dothelialbuty1phthalideOnacutecere-bralinfarction(VEGF)levelsofgrowthfactor.Method:68casesofpatients,simplerandomizationweredividedin—tOtheobservationgroup(35cases)andcontrolgroup(33cases),controlgroupweregivenoralaspirintablets,edaravoneintravenousneedles;theobservationgroupinthecontrolgroupbas5、edontheuseoforalButylphthalideSoftCapsules.ThetWOgroupsweretreatedfor14days.Comparisonoftwoclinicalefficacy,andinpatientsafterdiagnosisbeforetreatmentand14daysafterthedetectionoftwogroupsofnervefunctiondefectdegree(NIHSS)andserumVEGFleve1.Results:Intheobservationgroupaftertreatment,theclinicalto6、taleffectiveratewasalsohigherthanthatofthecontrolgroup(P7、andtheobservationgroupwaslowerthanthecontrolgroupaftertreatment(P<0.05).Conclusion:Buty1phthalidecanin—creasethelevelofVEGFintreatmentofacutecerebralinfarction.Keywords:Acutecerebralinfarction;Butylphthalide;VEGF;Efficacy丁苯酞
3、nfarctionandtheChangesofVascularEn-dothelialGrowthFactorSerumLevelsYIJiang,WEIJuan一,AIChibo,NIZhilinTheNinthHospitalofWuhanCity,Wuhan430060,China;RenminHospitalfoYunyangCountryofChongqingCity,Yunyang404500,China;Correspondingauthorobjective:Toobservetheclinicaltherapeuticeffectandserumvarcularen
4、dothelialbuty1phthalideOnacutecere-bralinfarction(VEGF)levelsofgrowthfactor.Method:68casesofpatients,simplerandomizationweredividedin—tOtheobservationgroup(35cases)andcontrolgroup(33cases),controlgroupweregivenoralaspirintablets,edaravoneintravenousneedles;theobservationgroupinthecontrolgroupbas
5、edontheuseoforalButylphthalideSoftCapsules.ThetWOgroupsweretreatedfor14days.Comparisonoftwoclinicalefficacy,andinpatientsafterdiagnosisbeforetreatmentand14daysafterthedetectionoftwogroupsofnervefunctiondefectdegree(NIHSS)andserumVEGFleve1.Results:Intheobservationgroupaftertreatment,theclinicalto
6、taleffectiveratewasalsohigherthanthatofthecontrolgroup(P7、andtheobservationgroupwaslowerthanthecontrolgroupaftertreatment(P<0.05).Conclusion:Buty1phthalidecanin—creasethelevelofVEGFintreatmentofacutecerebralinfarction.Keywords:Acutecerebralinfarction;Butylphthalide;VEGF;Efficacy丁苯酞
7、andtheobservationgroupwaslowerthanthecontrolgroupaftertreatment(P<0.05).Conclusion:Buty1phthalidecanin—creasethelevelofVEGFintreatmentofacutecerebralinfarction.Keywords:Acutecerebralinfarction;Butylphthalide;VEGF;Efficacy丁苯酞
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