应用低剂量舒芬太尼行分娩镇痛的效果观察-论文.pdf

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1、J实用临毒医鸯志2014年第18卷第5期·122·ournalofC1iniealMedicineinPractice’’⋯⋯应用低剂量舒芬太尼行分娩镇痛的效果观察叶小林(gtJll省彭州市妇幼保健院麻醉科，四川彭州，611930)摘要：目的探讨应用低剂量舒芬太尼对产妇行分娩镇痛的效果。方法将90例产妇随机分为观察组、对照I组及对照II组，每组3O例。3组均采用舒芬太尼镇痛，对照I组用量为3，观察组用量为5弘g，对照II组用量为7／*g。比较3组的镇痛效果、产妇分娩结局、不良反应和新生儿状态等指标。结果对照I组的镇痛起效时间显著长于观察

2、组和对照Ⅱ组(P<0．05)，首剂持续时间显著短于观察组和对照Ⅱ组(P<0．05)；镇痛前，3组患者的VAS评分无显著差异(P>O．05)；镇痛后30、60min，对照I组的VAS显著高于其他2组(P<0．05)；3组在顺产率、阴道助产率和剖宫产率方面比较无显著差异(P>0．05)；对照I组和观察组患者皮肤瘙痒、恶心呕吐、嗜睡、胎心改变等不良反应的发生率均显著低于对照Ⅱ组(P

3、能取得预期的效果。与高剂量舒芬太尼相比，低剂量舒芬太尼引发不良反应的概率较低，新生儿状态较好。关键词：分娩镇痛；舒芬太尼；低剂量；安全性中图分类号：R614文献标志码：A文章编号：1672—2353(2014)05—122—03DOI：10．7619~cmp．201405042SafetyandefficacyoflowdosesulfentanylinlaboranalgesiaYEXiaolin(DepartmentofAnesthesia，PengzhouMaternalandChildHealthCareHospital，Pen

4、gzhou，Sichuan，611930)ABSTRACT：ObjectiveToexploretheeffectoflowdosesulfentanylonlaboranalgesia．Methods90puerperaswererandomlydividedintoobservationgroup，controlgroupIandcontrolgroupII，30casesineachgroup．Sulfentanylwasusedforlaboranalgesiainallthegroups．Thedoseofsulfentany

5、linthecontrolgroup工，theobservationgroupandcontrolgroupI1were3／lg，5tLgand7respectively．Indexessuchasanalgesicefficacy，maternalbirthoutcomes，adversere—actionsandneonatalstatewerecomparedamongthreegroups．ResultsTheonsettimeofanalge—siainthecontrolgroup1wassignificantlylonge

6、rthanthatintheobservationgrouporthecontrolgroup11(P<0．05)，whilethefirstagentdurationwassignificantlyshorterthanthatintheob—servationgrouporthecontrolgroup1I(P<0．05)；beforetheanalgesia，therewasnosignificantdifferenceofVASscoreamongthreegroups(P>0．05)；atthetimeof30and60min

7、utesafteranalgesia，theVASscoreofthecontrolgroup1wassignificantlyhigherthanthatoftheothertwogroups(P<0．05)；therewerenosignificantdifferencesofthevagina1deliveryrate，assistantvaginaldeliveryrateandcesareansectionrateamongthethreegroups(P>0．05)；theincidenceratesoftheadverse

8、reactionssuchaspruritus，nauseaandvomiting，lethargyandfetalheartchangesofthewomeninthecontrolgroupIandth