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时间:2020-04-23
《伴躯体症状抑郁症患者皮质醇与述情障碍的相关性-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、行为医学与脑科学杂志2014年6月第23卷第6期ChinJBehavMed&BrainSci,June2014.V01.23.No.6·临床研究·伴躯体症状抑郁症患者皮质醇与述情障碍的相关性卢妍妍阎琳蒋珊李幼辉f摘要】目的探讨伴躯体症状的抑郁症患者血清皮质醇水平与述情障碍程度的相关性。方法采用放射免疫法测定30例伴躯体症状的抑郁症患者(躯体组)及30例不伴躯体症状的抑郁症患者(不伴组)晨起血清皮质醇水平,使用述情障碍量表(TAS一20)评定两组患者述情障碍。结果(1)躯体组血清皮质醇水平显著高于
2、不伴组[(533.88~144.10)I~mol/Lvs(458.27+82.87)~mol/L,P<0.01],差异有统计学意义。(2)躯体组述情障碍总分及识别情感障碍、描述情感障碍因子分高于不伴组[(67.13~6.96)分vs(62.03±7.14)分,(24.50~3.78)分vs(21.63~3.63)分,(15.30~2.69)分vs(13.57~2.03)分,均P<0.01],差异有统计学意义。(3)躯体组血清皮质醇水平与述情障碍总分正相关(r=0.596,P3、感障碍、描述情感障碍、外向性思维因子分正相关(r=0.391,0.435,0.452,均P<0.05)。(4)不伴组血清皮质醇水平与述情障碍总分正相关(r=0.418,P4、rumcortisolandalexithymiaindepressivepatientswithsomaticsymp·tomsLuYanyan,YanLin,JiangShah,LiYouhui.DepartmentD厂Psychiatry,TheFirstAffiliatedofZhengzhouUni—versity,Zhengzhou450052,China【Abstract】ObjectiveToinvestigatethecorrelationbetweenthelevelofse5、rumcortisolandalexithymiaindepressivepatientswithsomaticsymptoms.MethodsThemorninglevelofselumeortisolwasmeasuredwithra—dioimmunoassayin30depressivepatientswithsomaticsymptoms(somatizationgroup)and30depressivepatientswithoutsomaticsymptoms(non—somati6、zationgroup).TheseverityofalexithymiawasevaluatedwithTorontoalexi—thymiaScale(TAS-20).Results(1)Thelevelofserumcortisolinsomatizationgroupwassignificantlyhigherthanthatinnon—somatizationgroup((533.88~144.10)i~mol/Lvs(458.27~82.87)IxmoL/L,P7、hetotalTASscoreandthefactorscoreof“Dificultyinidentifyingfeelings”and“Dificultyindescribingfeelings”insomatizationgroupwereobviouslyhigherthanthoseinnon—somatizationgroup,respectively((67.13±6.96)vs(62.03+7.14),(24.50~3.78)vs(21.63~3.63),(15.30~2.69)8、vs(13.57~2.03),allP
3、感障碍、描述情感障碍、外向性思维因子分正相关(r=0.391,0.435,0.452,均P<0.05)。(4)不伴组血清皮质醇水平与述情障碍总分正相关(r=0.418,P4、rumcortisolandalexithymiaindepressivepatientswithsomaticsymp·tomsLuYanyan,YanLin,JiangShah,LiYouhui.DepartmentD厂Psychiatry,TheFirstAffiliatedofZhengzhouUni—versity,Zhengzhou450052,China【Abstract】ObjectiveToinvestigatethecorrelationbetweenthelevelofse5、rumcortisolandalexithymiaindepressivepatientswithsomaticsymptoms.MethodsThemorninglevelofselumeortisolwasmeasuredwithra—dioimmunoassayin30depressivepatientswithsomaticsymptoms(somatizationgroup)and30depressivepatientswithoutsomaticsymptoms(non—somati6、zationgroup).TheseverityofalexithymiawasevaluatedwithTorontoalexi—thymiaScale(TAS-20).Results(1)Thelevelofserumcortisolinsomatizationgroupwassignificantlyhigherthanthatinnon—somatizationgroup((533.88~144.10)i~mol/Lvs(458.27~82.87)IxmoL/L,P7、hetotalTASscoreandthefactorscoreof“Dificultyinidentifyingfeelings”and“Dificultyindescribingfeelings”insomatizationgroupwereobviouslyhigherthanthoseinnon—somatizationgroup,respectively((67.13±6.96)vs(62.03+7.14),(24.50~3.78)vs(21.63~3.63),(15.30~2.69)8、vs(13.57~2.03),allP
4、rumcortisolandalexithymiaindepressivepatientswithsomaticsymp·tomsLuYanyan,YanLin,JiangShah,LiYouhui.DepartmentD厂Psychiatry,TheFirstAffiliatedofZhengzhouUni—versity,Zhengzhou450052,China【Abstract】ObjectiveToinvestigatethecorrelationbetweenthelevelofse
5、rumcortisolandalexithymiaindepressivepatientswithsomaticsymptoms.MethodsThemorninglevelofselumeortisolwasmeasuredwithra—dioimmunoassayin30depressivepatientswithsomaticsymptoms(somatizationgroup)and30depressivepatientswithoutsomaticsymptoms(non—somati
6、zationgroup).TheseverityofalexithymiawasevaluatedwithTorontoalexi—thymiaScale(TAS-20).Results(1)Thelevelofserumcortisolinsomatizationgroupwassignificantlyhigherthanthatinnon—somatizationgroup((533.88~144.10)i~mol/Lvs(458.27~82.87)IxmoL/L,P7、hetotalTASscoreandthefactorscoreof“Dificultyinidentifyingfeelings”and“Dificultyindescribingfeelings”insomatizationgroupwereobviouslyhigherthanthoseinnon—somatizationgroup,respectively((67.13±6.96)vs(62.03+7.14),(24.50~3.78)vs(21.63~3.63),(15.30~2.69)8、vs(13.57~2.03),allP
7、hetotalTASscoreandthefactorscoreof“Dificultyinidentifyingfeelings”and“Dificultyindescribingfeelings”insomatizationgroupwereobviouslyhigherthanthoseinnon—somatizationgroup,respectively((67.13±6.96)vs(62.03+7.14),(24.50~3.78)vs(21.63~3.63),(15.30~2.69)
8、vs(13.57~2.03),allP
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