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时间:2020-04-21
《重症监护室患者血清降钙素原与 CRP 相关指标测定的临床意义.pdf》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、国际检验医学杂志2014年7月第35卷第14期IntJLabMed,July2014,Vo1.35,No.14·临床检验研究论著·重症监护室患者血清降钙素原与CRP相关指标测定的临床意义汪丽儿,杜菁,汪彤(皖南医学院附属第一医院:1.检验科;2.重症医学科,安徽芜湖241001)摘要:目的探讨血清降钙素原监测在判断重症患者是否并发感染的的价值。方法收集重症监护病房(ICU)188例患者分为感染组和未感染组,同时监测血清PCT、CRP、白细胞总数和中性粒细胞比值;感染组中41例患者连续1~6d动态测定PCT及相关指标,并进行统计学分析。结果重症感染组(
2、112例)和重症非感染组(76例)的年龄、PCT、CRP比较差异有统计学意义;除感染组PCT和CRP相关性比较有统计学意义外,其他指标比较差异无统计学意义(P>0.05);感染者中出院组(32例)和死亡组(9例),第1、2天两者PCT值比较P>0.05,第3~6天PCT值比较,差异有统计学意义(P<0.05)。结论血清PCT是判断重症患者感染与否的有效指标,独立并且明显优于传统的炎症指标,在重症患者中动态监测其水平对判断感染的控制情况具有一定价值。关键词:重症患者;PCT;CRP;感染D0I:10.3969/j.issn.1673—4130.2014
3、.14.014文献标识码:A文章编号:1673-4130(2014)14—1848—03ClinicalsignificanceofdeterminationofserumprocaicitoninandCRPrelatedindexesinICUpatientsWangLier,DuJing,WangTong(1.DepartmentofClinicalLaborototy;2.DepartmentofIntensiveCareMedicine,FirstAffiliatedHospital,WannanMedicalCollege,Wuhu,An
4、hui241001,China)Abstract:0bjectiveToexplorethevalueofserumproealeitonindetectioninjudgingwhetherseverepatientscomplicatewithinfection.Methods188patientsintheintensivecareunit(ICU)werecollectedanddividedintotheinfeetionandnon-infectiongroups.Theserumpr0calcit0nin(PCT),C—reactive
5、protein(CRP),totalnumberofwhitebloodcells(WBC)andneutrophilecellratioweresimultaneouslymonitored;41casesintheinfectiongroupdynamicallymonitoredPCTandrelatedindicatorsforcontinuous1—6dandthestatisticalanalysiswasconducted.ResultsTheage,PCTandCRPhadstatisticallysignificantdiffere
6、ncesbetweentheinfectiongroup(112cases)andnon—infectiongroup(76cases).ExceptthecorrelationofPCTandCRPintheinfectiongroupshowingstatisticalsignificance,thecomparisonoftheotherindicatorshadnostatisticaldifferences.Intheinfectors,thePCTvaluecomparisonbetweenon1dand2dinthehospitaldi
7、schargegroup(32cases)andthedeathgroup(9cases)showedP>0.05,thePCTvaluecomparisonbetweenon3~6dshowedP<0.05.ConclusionSerumPCTisaneffectiveindicatortOjudgewhetherse—vereinfectedpatienthasinfectionandissignificantlysuperiortOthetraditionalinflammatoryindicators.Dynamicallymonitorin
8、gthePCTlevelinthecriticalpatientshasacertainvaluetOjud
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