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1、米索前列醇舌下含服治疗产后出血临床疗效研究【摘要】目的:对比分析米索前列醇舌下含服治疗产后出血的临床疗效。方法:选取我院70例产妇,将产妇分为对照组和实验者,每组35人。实验组:孕妇娩出胎儿后立即含服米索前列醇4OOug,含至其自然溶解。对照组:孕妇娩出胎儿后立即静脉注射s缩宫素20Uo测量出血量的方法同一采用容积法和称重法,分别测量两组产后2h的出血量。将两种方法累加的血量作为最终产后2h的总失血量。结果:产后两组相比实验组第三产程时间、产后2h出血量、产后24h出血量均比对照组小,产后出血发生率实验组为2.
2、9%,对照组为17.1%,实验组产后出血发生率远小于对照组,差异显著具有统计学意义,P<0.05o米索前列醇和缩宫素对血压的作用不明显,对照组和实验组产妇使用前后血压、心律变化无明显差异。实验组部分产妇出现恶心和寒颤的现象,症状较轻微,产后4小时内自行消失,所以没有给予任何处理。结论:米索前列醇可以有效缩短第三产程、减少产后2小时出血量、降低出血率,减少产妇死亡率。【关键字】米索前列醇;缩宫素;产后出血;高危因素;第三产程Sublingualmisoprostolforpostpartumhemorrhage:
3、clinicalanalysisofWEIRong-fu(DepartmentofObstetricsandGynecology,thePeople"shospitalofDUJIANGYANCity,Sichuan611830)AbstractObjective:comparativeanalysisofmisoprostolsublingualtherapyforpostpartumhemorrhage.Methods:select70casesinourhospitalmaternalmaternal,w
4、illbedividedintothecontrolgroupandtheexperimenter,eachgroupof35people・Theexperimeritalgroups:pregnantchildbirthfetalsublingualmisoprostolimmediatelyafter400ug,includingtoitsnaturaldissolved.Controlgroup:pregnantwomendeliverbabiesimmediatelyafterintravenousin
5、jectionofoxytocin20Us.Measurementmethodforthesameamountofbleedingbyvolumetriemethodandgravimetricmethod,twogroupsweremeasuredtheamountofbleedingafter2h・Twokindsofmethodsthecumulativeoutputasthefinalpostpartum2Htotalbloodloss.Results:postpartumcomparedtwogrou
6、psexperimentaigroupthirddurationoflabor,postpartumbleedingvolumein2H,postpartumbleedingvolumein24hthanthecontrolgroup,therateofpostpartumhemorrhageinexperimentalgroupwas2.9%,17.1%inthecontrolgroup,theexperimentalgroupofpostpartumhemorrhagewasfarsmallerthanth
7、atofthecontrolgroup,differencehasstatisticalsignificance,P〈0・05.Misoprostolandoxytocinonbloodpressuredoesnotplayasignificantrole,theexperimentalgroupandthecontrolgroupbeforeandaftermaternaluseofbloodpressure,heartrhythmchangenodifference・Theexperimentalgroup
8、partofmaternalnauseaandchillsphenomenon,relativelyminorsymptoms,within4hourspostpartumdisappear,sodoesnotgiveanyprocessing.Conclusion:misoprostolcaneffectivelyshortenthethirdlabor,postpartumhemo