[精品]重组人胰岛素注射液治疗糖尿病74例的临床分析.doc

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1、重组人胰岛素注射液治疗糖尿病74例的临床分析重组人胰岛素注射液治疗糖尿病74例的临床分析【摘耍】目的：观察重组人胰岛素注射液治疗糖尿病的临床疗效。方法:将148例确诊为糖尿病的患者随机分为对照组和观察组,每组74例。在常规治疗的基础上，对照组采用中效人胰岛素(诺和灵30R)进行治疗，观察组采用重组人胰岛素注射液(优泌林30R)进行治疗，比较两组治疗前后空腹血糖、餐后2h血糖、糖化血红蛋白、总胆固醇、低密度脂蛋白胆固醇水平以及胰岛素抵抗指数等指标。结果：经过4个月治疗后，观察组和对照组的空腹血糖分别降低至(5.68±0.26)mmol/L和(6.83±0.41)mmol/L；餐后2h血糖

2、分别降低至(6.81+0.58)mmol/L和(8.83+0.43)mmoL/L；糖化血红蛋白分别降低至(5.38±0.17)%和(7.42±0・22)%。与治疗前比较，两组空腹血糖、餐后2h血糖、糖化血红蛋白以及其他临床指标如总胆固醇、低密度脂蛋白胆固醇水平等均得到显著改善，差异有统计学意义(P〈0.05),但观察组改善更加明显，与对照组比较，差异有统计学意义(卩〈0・05)。结论：重组人胰岛索注射液治疗糖尿病临床疗效显著，安全性较高，值得临床上推广应用。【关键词］重组人胰岛素注射液；糖尿病；临床疗效【Abstract】Objective：Toobservetheclinicalef

3、fectofrecombinanthumaninsulininjectionintreatmentofdiabetes,toprovidetheexperimentaldataandtheoreticalsupportforthefutureclinicalwork・Method：148patientswithdiabetesweredividedintocontrolgroupandobservationgrouprandomly,74casesineachgroup・Onthebasisofconventionaltreatment,thecontrolgroupweretreat

4、edwithinsulin(gnosis30r),theobservationgroupweretreatedwithrecombinanthumaninsulininjection(optimalsecreteLin30r)・Fastingbloodglucosebeforeandafterthetreatment,2hpostprandialbloodglucose,glycosylatedhemoglobin,totalcholesterol,lowdensityesterprotein,cholesterolandinsulinresistanceindexandotherin

5、dicatorsintwogroupswerecompared・Result：Afterfourmonthsaftertreatment,thefastingbloodglucoseinobservationgroupandcontrolgroupwerereducedto(5.68±0.26)mmol/Land(6.83+0.41)mmol/L；2hbloodglucoseaftermealinobservationgroupandcontrolgroupwerereducedto(6.81±0.58)mmol/Land(8.83+0.43)mmol/L；glycosylatedhe

6、moglobinwerereducedto(5.38±0.17)%and(7.42+0.22)%.Comparedwithbeforetreatment,fastingbloodglucose,2hpostprandialbloodglucose,glycosylatedhemoglobin,andotherclinicalindicatorssuchastotalcholesterol,lowdensityesterproteinsuchascholesterollevelsoftwogroupsweresignificantlyimproved,thediffereneewasst

7、atisticallysignificant(P<0.05),buttheobservationgroupimprovedmoresignificantly,comparedwithcontrolgroup,thedifferencewasstatisticallysignificant(P<0.05).Conclusion：Theclinicalcurativeeffectofrecombinanthumaninsulininjectioni