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1、中国组织工程研究与临床康复第14卷第8期2010–02–19出版JournalofClinicalRehabilitativeTissueEngineeringResearchFebruary19,2010Vol.14,No.8纳米药物载体的研究及临床应用金丽霞Researchandclinicalapplicationofnano-drugcarriersJinLi-xiaAbstractBACKGROUND:Comparedwithordinarypreparation,nano-drugcarriershavetheadvantagesofprolongeddrugeffec
2、ts,Departmentofincreasedtherapeuticeffectsandsmalltoxicity.However,reportsconcerningtheapplicationofnanoparticles,nano-liposomes,Pharmacy,SecondAffiliatedHospitalofpolymermicelles,nano-smartdrug,polymernano-bodymedicine,Dendrimersandothernanoscaledrugcarriersarefew.LiaoningMedicalOBJECTIVE:Tos
3、ummarizethecharacteristics,typesandpreparationmethodsofnano-drugcarriers,andtoelucidateitsUniversity,Jinzhouresearchprogress.121000,LiaoningMETHODS:TheMedlinedatabasewassearchedbycomputerwithkeywordsof“Nano-drugcarriers,nanoparticles,Province,Chinanano-liposomes,clinicalapplication”tofindliter
4、aturespublishedbetweenJanuary1991toDecember2009,andthelanguageJinLi-xia,ChiefwaslimitedtoEnglish.Simultaneously,articlespublishedfromJanuary1994toDecember2009weresearchedinChinesePharmacist,JournalFull-textdatabasewiththesamekeywords,andthelanguagewaslimitedtoChinese.Inclusioncriteria:①Article
5、sareDepartmentofcloselyrelatedtotheresearchofnano-drugcarrier.②RelatedresearchespublishedoncorejournalsinthelatestyearswerePharmacy,SecondAffiliatedHospitalofpreferentialinselection.Exclusioncriteria:①Repeatabilitystudy.②Metaanalysis.LiaoningMedicalRESULTSANDCONCIUSION:Atotalof360documentswere
6、seizedbyprimaryscreen,finally28sub-standardliteraturesUniversity,Jinzhouenteredfurtheranalysis,including25reviewsand3clinicalorbasicexperiments.Thenano-drugcarriersarecharacterizedby121000,Liaoningspecificity,targeting,accurateandabsorbable,whichcanbeusedinpreventingandcuringdisease.Thecombina
7、tionofnanoProvince,China84890850@qq.comcarriersandspecificdrugscanpromotethedevelopmentofnano-biotechnology,andprovideareliablebasisforclinicaldiagnosisandtreatment.Received:2009-12-29Accepted:2010-01-18JinLX.Researchandclinicalapplicat
