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时间:2017-12-08
《苯磺酸氨氯地平联合替米沙坦应用对老年原发性高血压患者血压晨峰和血压变异性的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、782ChineseJournalofClinicalMedicine,2013.Vo1.20,No.6中国临床医学2()13年12月第2()卷第6期论著苯磺酸氨氯地平联合替米沙坦应用对老年原发性__-__0同口血压患者血压晨峰和血压变异性的影响奚东珠丁立民刘庶珠王大伟李耕慧李冬冬仉玉泉(黑龙江省齐齐哈尔市第一医院干部病房,黑龙江齐齐哈尔161005)摘要目的:探讨苯磺酸氨氯地平联合替米沙坦对老年原发性高血压患者血压晨峰及血压变异性的影响。方法:选择2011年3月2()12年3月齐齐哈尔市第一医院收治的老年原发性高血压患者48例,给予苯磺酸氨氯地平(5mg/d)联合替米沙坦
2、(40mg/d)治疗4周。治疗前后分别进行24h动态血压监测,采用自身对照研究的方法对比分析治疗前后患者血压晨峰及血压变异性的差异。结果:与治疗前比较,老年原发性高血压患者治疗后的24h平均收缩压、24h平均舒张压、白昼平均收缩压、白昼平均舒张压、夜间平均收缩压、夜间平均舒张压、血压晨峰、24h收缩压标准差、24h舒张压标准差、24h收缩压变异系数、24h舒张压变异系数均下降,治疗前后比较差异均有统计学意义(P3、患者的血压晨峰及血压变异性。关键词高血压;血压晨峰;血压变异性;苯磺酸氨氯地平;替米沙坦中图分类号R544.1文献标识码AEffectsofAmlodipineBesylateCombinedwithTelmisartanonMorningBloodPressureSurgeandBloodPres—sureVariabilityinElderlyPatientswithEssentialHypertensionXIDongzhuDINGLiminLIUShuzhuNGDaweiLIGenghuiLIDongdongZHANGYuquanCadreWr,TheFirstHo4、spitalo.,Qiqihar,Qiqihar161005,ChinaAbstractObjective:Toinvestigatetheeffectsofamlodipinebesylatecombinedwithtelmisartanonmorningbloodpressuresurge(MBPS)andbloodpressurevariability(BPV)inelderlypatientswithessentialhypertension.Methods:Atotalof48elderlypatientswithessentialhypertensionwere5、treatedwithamlodipinebesylate(5mg/d)combinedwithtelmisartan(40mg/d)for4weeks.And24hambulatorybloodpressuremonitoring(ABPM)wasperformedbeforeandaftertreatment.ThedifferencesofMBPSandBPVbeforeandaftertreatmentinpatientswereanalyzedbyusingself-controlstudy.Results:Inelderlypatientswithessenti6、alhypertension,comparedwithbeforetreatment,24hmeansystolicbloodpressure,24hmeandiastolicbloodpressure。daytimemeansystolicbloodpressure,daytimemeandiastolicbloodpressure,nighttimemeansystolicbloodpressure,nighttimemeandiastolicb'loodpressure,MBPS,24hsystolicstandarddeviation,24hdiastolicsta7、ndarddeviation,24hsystoliccoefficientofvariationand24hdiastoliccoefficientofvariationwereloweraftertreatment.Thedifferencesweresignificant(P<0.05).Tota1cholesteroIandlOWdensitylipoproteincholesterolaftertreatmentwerelowerthanbeforetreatmentandthedifferenceswer
3、患者的血压晨峰及血压变异性。关键词高血压;血压晨峰;血压变异性;苯磺酸氨氯地平;替米沙坦中图分类号R544.1文献标识码AEffectsofAmlodipineBesylateCombinedwithTelmisartanonMorningBloodPressureSurgeandBloodPres—sureVariabilityinElderlyPatientswithEssentialHypertensionXIDongzhuDINGLiminLIUShuzhuNGDaweiLIGenghuiLIDongdongZHANGYuquanCadreWr,TheFirstHo
4、spitalo.,Qiqihar,Qiqihar161005,ChinaAbstractObjective:Toinvestigatetheeffectsofamlodipinebesylatecombinedwithtelmisartanonmorningbloodpressuresurge(MBPS)andbloodpressurevariability(BPV)inelderlypatientswithessentialhypertension.Methods:Atotalof48elderlypatientswithessentialhypertensionwere
5、treatedwithamlodipinebesylate(5mg/d)combinedwithtelmisartan(40mg/d)for4weeks.And24hambulatorybloodpressuremonitoring(ABPM)wasperformedbeforeandaftertreatment.ThedifferencesofMBPSandBPVbeforeandaftertreatmentinpatientswereanalyzedbyusingself-controlstudy.Results:Inelderlypatientswithessenti
6、alhypertension,comparedwithbeforetreatment,24hmeansystolicbloodpressure,24hmeandiastolicbloodpressure。daytimemeansystolicbloodpressure,daytimemeandiastolicbloodpressure,nighttimemeansystolicbloodpressure,nighttimemeandiastolicb'loodpressure,MBPS,24hsystolicstandarddeviation,24hdiastolicsta
7、ndarddeviation,24hsystoliccoefficientofvariationand24hdiastoliccoefficientofvariationwereloweraftertreatment.Thedifferencesweresignificant(P<0.05).Tota1cholesteroIandlOWdensitylipoproteincholesterolaftertreatmentwerelowerthanbeforetreatmentandthedifferenceswer
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