止痛消炎膏联合肝素钠乳膏外涂治疗医源性新生儿钙盐沉积症的疗效观察.doc

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1、止痛消炎膏联合肝素钠乳膏外涂治疗医源性新生儿钙盐沉积症的疗效观察doi：10.3969/j.issn.1007-614x.2014.21.61摘要目的：探讨止痛消炎膏联合肝索钠乳膏外涂治疗医源性新生儿钙盐沉积症的临床疗效。方法：2012年4月-2014年3月收治医源性新生儿钙盐沉积症患儿30例，随机分为试验组和对照组，各15例。试验组在钙盐沉积处用0.9%氯化钠注射液清洗干净后先涂抹肝素钠乳膏并适当局部按摩后用止痛消炎膏敷于患处，3次/日；对照组用透明质酸酶局部封闭。结果：试验组全部治愈，疗程18〜29天，平均（23・7±3.5）天；对照组治愈率86.7%

2、,疗程47~56天，平均（52.2±2.7）天，两组比较差异均有统计学意义（P〈0・05）。结论：止痛消炎膏联合肝素钠乳膏外涂治疗医源性新生儿钙盐沉积症治愈率高，疗程短，可行性较强，疗效好，值得临床推广。关键词止痛消炎膏肝索钠乳膏新生儿钙盐沉积症Theobservationofthecurativeeffectofanti-inf1ammatoryanalgesiccreamcombinedwithheparinsodiumcreamcoatedinthetreatmentofiatrogenicneonatalcalciumsaltdepositiond

3、iseaseZhaoLei,HouYupei,LiDanfengNeonatalIntensiveCareUnit（NICU）,theChildresHospitalofZheng/houCity,Henan450053AbstractObjective:Toinvestigatetheclinicaleffectofanti-inflanimatoryanalgesiccreamcombinedwithheparinsodiumcreamcoatedinthetreatmentofiatrogenicneonatalcalciumsaltdepositi

4、ondisease.Methods：30casesofiatrogenicneonataicalciumsaltdepositiondiseasewereselectedfromApril2012toMarch2014.Theywererandomlydividedintotheexperimentalgroupandthecontrolgroupwith15casesineach.Theexperimentalgroupwerewashedthedepositionofcalciumsaltscleaningusingphysiologicalsalin

5、e,smearedheparinsodiumcreamatfirstandappropriatelocalmassage,thenapplyedanti-inflammatoryanalgesiccreamtoaffectedarea,3times/day.Thecontrolgroupwerepartialclosedwithhyaluronidase.Results：Theexperimentalgroupwereallcured；thecourseoftreatmentwas18~29days,withanaverageof23.7+3.5days.

6、Thecurerateofthecontrolgroupwas86.7%；thecourseoftreatmentwas47~56days,withanaverageof52.2±2.7days.Thedifferencewerestatisticallysignificantbetweenthetwogroups（卩〈0.05）.Conelusion:Analgesicanti-inflammatoryointmentcombinedwithheparinsodiumcreaminthetreatment,ofiatrogenicneonataicalc

7、iumsaltdepositiondiseasehavehighcurerate,且ndalsowithshorttreatmentcourse,practical,andgoodcurativeeffect,soitisworthyofclinicalpromotion.KeywordsAnti-inflammatoryanalgesiccream；Heparinsodiumcream；Iatrogenicneonatalcalciumsaltdepositiondisease新生儿低钙血症是儿科常见病症。静脉补钙不可避免，钙剂外渗又是临床常遇到的问题，

8、医源性新生儿钙盐沉积症，多发生于长期输液的新生儿和早产儿［1］。新