三维斑点追踪成像评价小儿膜周部室间隔缺损左心室局部收缩功能-论文.pdf

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1、第45卷第7期温州医科大学学报Vb1．45NO．72015年7月JournalofWenzhouMedicalUniversityJu1．2015■潮■三维斑点追踪成像评价d,JL膜周部室间隔缺损左心室局部收缩功能王珍，田新桥，付定虎，刘敏，詹坤高，吴道珠(温州医科大学附属第二医院超声科，浙江温州325027)[摘要]目的：应用三维斑点追踪成像(39．STI)技术定量评价小儿膜周部室间隔缺损(PmVSD)左心室局部收缩功能变化。方法：PmVSD,]、儿4o例(PmVSD组)，年龄、性别相匹配的对照组35例。采集左心室三维全容积图像，运用3D-STI技术测量2组对象收缩期

2、左心室l6节段的圆周、纵向、径向峰值应变，比较2组间各参数的差异性，并进一步分析其与左室射血分数、左室容量负荷参数的相关性。结果：PmVSD组左室各节段三个方向峰值应变测值大多数均较正常组增大，其中前、侧壁基底段和侧、后壁中间段的纵向峰值应变及侧壁、下间隔壁中间段的圆周峰值应变和侧壁、下间隔壁中间段及基底段的径向峰值应变差异有统计学意义(P<0．05)；纵向、圆周、径向峰值应变均分别与左心室舒张末容积呈正相关。结论：3D．STI技术可敏感地检出PmVSD,]、几左心室局部收缩功能的异常改变，具有一定的临床应用价值。[关键词]超声心动描记术；三维斑点追踪；室间隔缺损；心室

3、功能，左[中图分类号]R445．1IX献标志码]ADOI：10．3969~．issn．2095．9400．2015．07．009Evaluationofregionalleftventrieularsystolicfunctioninpediatricpatientswithperimembranousven．tricularseptaldefectusingthree-dimensionalspeckletrackingimagingWANGZhen．TIANXinqiao．FUDinghu，LIUMin，ZHANKungao，WUDaozhu．Departmento

4、fUltrasonography,theSecondAfiliatedHospitalofWenzhouMedicalUniversity,Wenzhou，325027墨圃_Objective：Toevaluateregiona1leftventricular(LV)systolicfunctioninpediatricwithperi．membranousventricularseptaldefect(PmVSD)usingthree-dimensionalspeckletrackingimaging(3D-STI)．Methods：Transthoracicfull

5、·-volume3Dimageswereobtainedin40patientswithPmVSDand35age·-andsex-matchedcontrols．Thefull—volume3Ddatasetswererecorded，3D-STIanalysisprovidedmeasuresofpeakcircumferential，radial，andlongitudinalstrainin16LVsegments(6basal，6mid，and4apica1)，leftventricularendsystolicandenddiastolicvolumes(L

6、VESVandLVEDV)wereautomaticmeasured．Thestrainvalueswerecomparedbetweenthetwogroups．CorrelationanalysisbetweenLVEDV,LVESVIⅣEFandLVsystolicstrainvaluesweremaderespectively．Results：Comparedwiththecontrolgroup，multidirectionalstrainsforalmostlyallsegmentsstrainvalueswerehigherinpatientswithPm

7、VSD，especiallythepeaksystoliclongitudinalstraininLVanterior,lateralwallbasalsegments．1ateral，posteriorwallmiddlesegmentsandthepeaksystoliccircum—ferentialstraininLVlatera1．inferior-septumWallmiddlesegmentsandpeaksystolicradialstraininLVinferior-septum，lateralwallmiddleseg