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时间:2020-04-12
《分子影像SPECT/CT对乳腺癌骨转移的临床应用价值.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、中国临床医学影像杂志2015年第26卷第7期JChinClinMedImaging,2015,Vo1.26,No.7·465·分子影像SPECT/CT对乳腺癌骨转移的临床应用价值董科,傅健飞,楼菁菁,刘江(金华市中心医院核医学科,浙江金华321000)[摘要】目的:探讨分子影像SPECT/CT对乳腺癌骨转移的临床应用价值。方法:回顾性分析多层螺旋cT与SPECT/CT融合显像对68个疑似乳腺癌骨转移病灶的检查结果,进行统计学检验。结果:经临床确诊乳腺癌骨转移的55个病灶中:MSCT诊断的敏感度为78.2%(43/55),特异性为92
2、.3%(12/13),准确性为80.9%(55/68);SPECT/CT融合显像诊断敏感度为96.4%(53/55),特异性为76.9%(10/13),准确性为92.6%(63/68)。2种检查方法的敏感度、准确性差异有统计学意义(P3、2015)07-0465—04TheclinicalapplicationvalueofmolecularimagingSPECT/CTforbonemetastasesfrombreastcancerDONGKe,FUJian-fei,LOU)ing_jing,LIUJiang(DepartmentofNuclearMedicine,JinhuaCentralHospital,JinhuaZhejiang321000,China)Abstract:Objective:Toinvestigatetheclinicalapplicat4、ionvalueofthemolecularimagingSPECT/CTforbonemetastasesofbreastcancer.Methods:BothMSCTandSPECT/CTimagingdataof68suspiciousbonemetastaseslesionsofbreastcancerwereretrospectivelyanalyzedandcompared,andthestatisticscheckoutwasearriedout.Resluts:Amongthe55bonemetas—tasesles5、ionsofbreastcancer,sensitivity,specificityandaccuracyofbonemetastasesdiagnosedbyMSCTwere78.2%(43/55),92_3%(12/13)and80.9%(55/68);andsensitivity,specificityandaccuracyofbonemetastasesdiagnosedbySPECT/CTwere96.4%(53/55),76.9%(10/13)and92.6%(63/68).Forthedifferenceofthese6、nsitivityandaccuracy,therewasstatisticallysignifi—cancebetweenMSCTandSPECTmethods(P<0.05),andthespecificityofbothmethodswasnodiference.Conclusions:Com—paringwithMSCT,theSPECT/CTfusionimagingcanimprovethesensitivityandaccuracyofthebonemetastasesdiagnosisofbreastcancer,a7、ndhavingbetterclinicalapplicationvalue.Keywords:Breastneoplasms;Neoplasmmetastasis;Tomography,emission—computed,single-photon骨骼是乳腺癌远处转移的最常见部位。及早发例、髓样癌1例,并排除其他恶性肿瘤病史。对全身现转移灶对乳腺癌临床分期及治疗方案的选择具有骨显像有异常的共计68个疑似骨转移病灶,均行重要意义。多层螺旋CT具有较高的密度分辨力,但MSCT及SPECT/CT融合显像,且2种检查方法间隔检查范围局限,8、对早期骨转移灶敏感性较低。在全身时间<2周;除9个疑似骨转移病灶经活检病理诊断平面骨显像基础上,配备有诊断CT的SPECT/CT既外,其余病灶均为2种以上影像技术综合诊断并临有较高的敏感度,又有效地提高了诊断骨骼病变的床随访时间>3月
3、2015)07-0465—04TheclinicalapplicationvalueofmolecularimagingSPECT/CTforbonemetastasesfrombreastcancerDONGKe,FUJian-fei,LOU)ing_jing,LIUJiang(DepartmentofNuclearMedicine,JinhuaCentralHospital,JinhuaZhejiang321000,China)Abstract:Objective:Toinvestigatetheclinicalapplicat
4、ionvalueofthemolecularimagingSPECT/CTforbonemetastasesofbreastcancer.Methods:BothMSCTandSPECT/CTimagingdataof68suspiciousbonemetastaseslesionsofbreastcancerwereretrospectivelyanalyzedandcompared,andthestatisticscheckoutwasearriedout.Resluts:Amongthe55bonemetas—tasesles
5、ionsofbreastcancer,sensitivity,specificityandaccuracyofbonemetastasesdiagnosedbyMSCTwere78.2%(43/55),92_3%(12/13)and80.9%(55/68);andsensitivity,specificityandaccuracyofbonemetastasesdiagnosedbySPECT/CTwere96.4%(53/55),76.9%(10/13)and92.6%(63/68).Forthedifferenceofthese
6、nsitivityandaccuracy,therewasstatisticallysignifi—cancebetweenMSCTandSPECTmethods(P<0.05),andthespecificityofbothmethodswasnodiference.Conclusions:Com—paringwithMSCT,theSPECT/CTfusionimagingcanimprovethesensitivityandaccuracyofthebonemetastasesdiagnosisofbreastcancer,a
7、ndhavingbetterclinicalapplicationvalue.Keywords:Breastneoplasms;Neoplasmmetastasis;Tomography,emission—computed,single-photon骨骼是乳腺癌远处转移的最常见部位。及早发例、髓样癌1例,并排除其他恶性肿瘤病史。对全身现转移灶对乳腺癌临床分期及治疗方案的选择具有骨显像有异常的共计68个疑似骨转移病灶,均行重要意义。多层螺旋CT具有较高的密度分辨力,但MSCT及SPECT/CT融合显像,且2种检查方法间隔检查范围局限,
8、对早期骨转移灶敏感性较低。在全身时间<2周;除9个疑似骨转移病灶经活检病理诊断平面骨显像基础上,配备有诊断CT的SPECT/CT既外,其余病灶均为2种以上影像技术综合诊断并临有较高的敏感度,又有效地提高了诊断骨骼病变的床随访时间>3月
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