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时间:2017-12-07
《不同麻醉方式对老年高血压患者上腹部术中应激反应的探讨》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、临床合理用药2o13年l1月第6卷第11期中ChinJofChmcMRationalDrugUse。November2013,VoL6No.11B·25··论著·不同麻醉方式对老年高血压患者上腹部术中应激反应的探讨张占军,胡腾,周华【摘要】目的探讨不同麻醉方式对老年高血压上腹部手术患者术中应激反应的影响。方法8O例老年高血压手术患者,按照平均性原则分为2组,每组患者30例,即观察I组(单纯全身麻醉)与观察Ⅱ组(全身麻醉与硬膜外阻滞联合)。2组患者均通过4个阶段(术前、切皮时、手术60min、拔管时)对肾上腺素、皮质醇、内皮素含量以及
2、HR(心率值)、血流动力学MAP(平均动脉压值)进行测定。结果观察Ⅱ组患者在手术60rain及拔管时的皮质醇及肾上腺素水平明显低于观察I组,差异有统计学意义(P<0.05);且在切皮时、手术60min、拔管时的内皮素水平也明显低于观察I组,差异有统计学意义(P<0.05)。观察Ⅱ组患者的HR在切皮时、手术50rnin、拔管时明显低于观察I组,差异有统计学意义(P<0.05);且拔管时的MAP也明显低于观察I组,差异有统计学意义(P<0.05)。结论全身麻醉与硬膜外阻滞联合应用可以有效控制高血压老年患者术中的应激反应,临床值得应用与推
3、广。【关键词】麻醉方式;老年人;高血压;应激反应【中图分类号】R614【文献标识码】A【文章编号】1674—3296(2013)llB一0025—02Studyofdifferentanestheticmethodsonthestressl-~ponsetoabdominalsurgeryinelderlypatientswithhyperten-sionZHANGZhan-jun,HU,ZHOUHua.ThePeoplesHospitalofJ/aozuo,Henan454150,China【Abstract】ObjectiveT
4、oinvestigatetheefectofdiferentanestheticmethodsonthestressresponsetoabdominalsurgeryinelderlypatientswithhypertension.Methods80Ca8C8ofelderlypatientsweredividedinto2groupsaccordingtotheaverageprinciple,eachof40cases:observationgroupI(generalanesthesia)andobservationgro
5、upII(epiduralblockcom—binedwitllgeneralanesthesia).Theadrenaline,cortisol,endothelincontentandHR(heartrate),hemodynamicparametersofmeanarterialpressure(MAP)weredeterminedtIlIoug}lthe4stages(beforesurgery,skinincision,operationwithin60rain,ex-tubation)inthe2groups.Resul
6、tsThecortisolandepinephrinelevelswhenthesurgeryfor60minandwhenthetubedrawingoftheobservationgroupII眦lowerthanthoseoftheobservationgroupI.andthediferenceswerestatisticallysignificant(P<0.05);theendothelinlevelwhencuttingskin,thesurgeryfor60minandthetubedrawingoftheobser
7、vationgroupI1waslowerthanthatoftheobservationgroupI,andthediferencewasstatisticallysignificant(P<0.05);theHRwhencuttingskin,thesurgeryfor60minandthetubedrawingoftheobservationgroupl1waslowerthanthatoftheobservationgroupI,andthediferencewasstatisticallysignificant(P<0.0
8、5);theMAPwhenthetubedrawingoftheobservationgroupI1waslow-erthanthatoftheobservationgroupI,andthediferencewasstatistic
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