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1、普米克令舒联合特布他林治疗慢阻肺急性加重期的疗效观察陈勇叶永青刘国栋谭经福冼宏(广东省河源市人民医院河源517000)摘要:目的:临床探究特布他林、普米克令舒联合治疗慢阻肺急性加重期的可行性、优越性。方法:选取我院2015年X月〜2016年7月80例诊断为慢阻肺急性加重期入院治疗患者,按双盲法随机分为对照组40例、治疗组40例。对照组使用普米克令舒药物,治疗组加用特布他林,观察患者症状改善情况,同时对治疗前后肺功能改善、血气恢复情况进行统计。结果:治疗前两组肺功能差异无意义,P>0.05;用药后治疗组较对照组肺功能恢复更好,P<0.05o治疗前两组血气差异无意义,P>0.
2、05;用药后治疗组较对照组血气恢复更好,P<0.05o治疗组总有效率为95.0%,对照组的为82.5%,治疗组较对照组患者病症恢复效果更好,P<0.05。结论:临床对慢阻性肺急性加重期患者治疗时,为促进患者肺通气功能、血气恢复,可选择特布他林、普米克令舒联合用药,患者恢复好、治疗效果理想。关键词:慢阻肺急性加重期;特布他林;普米克令舒ClinicalEffectofPulmicortandTerbutalineintheTreatmentofAcuteExacerbationofChronicObstructivePulmonaryDiseaseCHENYong,YEYo
3、ng-qing,LIUGuo-dong,TANJing-fu,XIANHong(TheHeyiianPeopledHospital,Guangdong517000)Abstract:Objective:TostudytheclinicalfeasibilityandadvantagesofTerbutalineandPulmicortinthetreatmentofacuteexacerbationofchronicobstructivepulmonarydisease(COPD).Method:80PatientswithacuteexacerbationofCOPDt
4、reatedfromAugust2015toJuly2016inourhospital,wererandomlydividedintotwogroups,40caseseachgroup・ThecontrolgrouptookPulmicort,thetreatmentgrouptookPulmicortandTerbutaline・Theclinicalsymptoms,pulmonaryfunctionandbloodgaswereobserved・Result:Beforetreatment,thepulmonaryfiinctionoftwogroupswasno
5、significantdifference(P>0.05),aftertreatment,thepulmonaryfunctionofthetreatmentgroupwasbetterthanthatofthecontrolgroup(P<0.05).Beforetreatment,thebloodgasoftwogroupswasnosignificantdifference(P>0.05),aftertreatment,thebloodgasofthetreatmentgroupwasbetterthanthatofthecontrolgroup(P<0.05).T
6、heclinicaleffectiverateofthetreatmentgroup(95.0%)washigherthanthecontrolgroup(82.5%)(P<0.05).Conelusion:ForpatientswithacuteexacerbationofCOPD,thecombinedtherapyofTerbutalineandPulmicortcanimprovethepulmonaryventilationfunctionandbloodgas,andpromotethepatient'sfastrecovery.Keywords:Acutee
7、xacerbationofCOPD;Terbutaline;Pulmicort中图分类号:R563.9文献标识码:B慢性阻塞性肺疾病发病隐匿、发展缓慢,若不及时治疗病情迁延不愈可引发呼吸衰竭、肺心病,此病发病与空气环境、支气管炎、肺气肿、粉尘等有关,中老年为疾病高发年龄段,相关数据统计显示中老年人疾病发病率在10%左右⑴。此病为气流阻塞性疾病,因气道、肺部受多种因索影响导致炎性反应强烈,从而引发疾病,此病致病因索众多至今未全面了解,患者临床多表现为咳嗽且表现为晨间持续性咳嗽,夜间偶尔阵咳,同时在体力劳动后出现气虚、呼吸困难、气