重症颅脑损伤患者肺部感染病原菌分析.pdf

《重症颅脑损伤患者肺部感染病原菌分析.pdf》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。

1、中华医院感染学杂志2014年第24卷第9期ChinJNosocomiolVo1．24No．92014·2127·doi：10．11816／cn．ni．2014—132213论著重症颅脑损伤患者肺部感染病原菌分析周咏梅，陈伟军，程红英(浙江省新昌县中医院检验科，浙江新昌县312500)摘要：目的探讨重症颅脑损伤ICU内肺部感染病原菌检验分析的临床应用，为其临床研究提供参考依据。方法选取86例因重症颅脑损伤入住医院ICU且发生肺部感染的患者，所有患者均详细记录基本信息，根据病情给予相应治疗，同时留取其痰

2、液进行培养及药敏试验；采用SPSS12．0软件进行统计分析。结果86例患者中共分离出病原菌94株，其中革兰阴性菌55株占58．5％，以肺炎克雷伯菌为最多，革兰阳性菌29株占30．9，以金黄色葡萄球菌最多，真菌1O株占10．6，以白色假丝酵母菌最多；革兰阴性菌对头孢哌酮／舒巴坦最敏感，敏感率80．0，其次为亚胺培南，敏感率74．5；革兰阳性菌对万古霉素最敏感，敏感率96．6，其次为氨苄西林，敏感率82．8，真菌对氟康唑最敏感，敏感率8O．0，其次为伏立康唑，敏感率60．0。结论重症颅脑损伤患者肺部感染

3、应尽早采集标本进行细菌鉴定及药敏试验，明确病原学诊断，有针对性地使用敏感的抗菌药物。关键词：重症颅脑损伤；肺部感染；重症监护病房；病原菌中图分类号：R378文献标识码：A文章编号：1005—4529(2014)09—2127—03PathogenscausingpulmonaryinfectionsinpatientswithseverecraniocerebralinjuriesZHOUYong-mei，CHENWei—jun，CHENGHong—ying(XinchangCountyChines

4、eMedicineHospital，Xinchang，Zhejiang312500，China)Abstract：OBJECTIVEToexplorethedistributionofpathogenscausingpulmonaryinfectionsinICUpatientswithseverecraniocerebralinjuriesSOastoprovidebasesforclinicalstudy．METHODSTotally86patientswhowerehospitalizedfo

5、rseverecraniocerebralinjuriesandcomplicatedwithpulmonaryinfectionswereenrolledinthestud—y，thenthebasicinformationofallthepatientswasrecordedindetail，thecorrespondingtherapieswereperformedaccordingtothecondition，thesputumspecimensweresampledforculture，t

6、hedrugsusceptibilitytestingwascarriedout，andthestatisticalanalysiswasperformedwiththeuseofSPSS12．0software．RESULTSAtotalof94strainsofpathogenshavebeenisolatedfromthe86patients。including55(58．5)strainsofgram-negativebacte—ria，29(30．9％)strainsofgram—posi

7、tivebacteria，and10(10．6)strainsoffungi；theKlebsiellapneumoniaewasdominantamongthegram-negativebacteria，theS￡口声Zoc0ccsaureuswasthepredominantspeciesofthegram-positivebacteria，andtheCandidaalbicanswasthemostcommonspeciesofthefungi．Thegram-negativebacteri

8、aweremostsusceptibletocefoperazone-sulbactamwiththesusceptibilityrateof8O．0，followedbyimi—penem(74．5％)；thegram-positivebacteriaweremostsusceptibletovancomycinwiththesusceptibilityrateof96．6，followedbyampicillin(82．8)；thefungiwerethemost