大黄附子汤治疗慢性肺心病并发心力衰竭的疗效观察.pdf

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1、泰山医学院学报JOURNALOFTA1SHANMEDICALCOLLEGEVoL35No．42014大黄附子汤治疗慢性肺心病并发心力衰竭的疗效观察林宏张智琳蔡飙(广州市中医医院，广东广州510130)摘要：目的观察大黄附子汤治疗慢性肺心病并发心力衰竭的临床疗效。方法将患者随机分为西药对照组和联合治疗组，两者均用西医标准化方案治疗，给予有效的抗生素、吸氧、平喘、祛痰及利尿等常规综合治疗，联合治疗组患者则在此基础上加用大黄附子汤，疗程10天。用药前后分别检测患者的LVEF和血清BNP水平。结果两组患者经治疗后，LVEF较治疗前有明显上升(P<0．05)，BNP较治疗前有

2、明显下降(P<0．05)，而联合治疗组的两项指标均较西药对照组有显著的改善(P<0．05)。结论大黄附子汤对慢性肺心病并发心力衰竭有一定的治疗作用，西医常规治疗联合大黄附子汤治疗较单纯西医治疗的疗效更佳。关键词：慢性肺心病；心力衰竭；大黄附子汤中图分类号：12563．8文献标识码：A文章编号：1004-7115(2014)04-0293-03doi：10．3969／j．issn．1004—7115．2014．04．017ThecurativeefectobservationaboutRhubarbandPreparedAconitedecoctioninthetre

3、atmentofchronicpulmonaryheartdiseasecomplicatedwithheartfailureLINHongZttANGZhi—linCAIBiao(GuangzhouHospitalofTCM，Cuangzhou510130，China)Abstract：Objective：ToobservetheclinicalcurativeeffectofRhubarbandPreparedAconiteDecoctioninthetreatmentofchronicpulmonaryheartdiseasecomplicatedwithhe

4、artfailure．Methods：Patientswererandomlydividedintowesternmedicinegroup(controlgroup)andcombinedtreatmentgroup，bothwesternmedicinestandardizedtreatment，givenefectiveantibiotics，oxygeninhalation，asthma，expectorantanddiureticandotherconventionaltreatment，thetreatmentgrouppa—tientsbasedont

5、heuseofRhubarbandPreparedAconiteDecoction，treatmentcoursewas10days．PatientswithLVEFandserumBNPlevelsweremeasuredbe~reandaftertreatment．Results：Twogroupsofpatientsaftertreatment，LVEFincreasedcomparedwiththosebeforetreatment(P<0．05)，BNPdecreasedsignificantlycomparedwiththosebeforetreatme

6、nt(P<0．05)，andtwoindexesofcombinedtreatmentgroupwerelowerthanthewesternmedicinegroupwereimprovedsignificantly(P<0．05)．Conclusion：RhubarbandPreparedAconiteDecoctionhasefectinthetreatmentofchronicpulmonaryheartdiseasecomplicatedwithheartfailure，routinetreatmentofWesternmedicinecombinedwi

7、thRhubarbandPreparedAconiteDecoctionwasbettercurativeefectthanpurewesternmedicinetreatment．Keywords：chronicpulmonaryheartdisease；heartfailure；RhubarbandPreparedAconiteDecoction慢性肺源性心脏病(肺心病)是指由肺部胸廓肺血管痉挛等因素造成肺动脉高压，常伴有心肺功或肺动脉的慢性病变引起的肺循环阻力增高，致使能衰竭，预后较差。目前的西医治疗主要是消炎、化肺动脉高压和右心室肥大，或伴有右心衰竭心脏