冠状病毒Coronavirusl论文-2002 Enteric Coronavirus Infection in a Juvenile Dromedary (Camelus Dromedarius).pdf

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1、BriefCommunications44112.Stallnecht,DE:1999,VSV-NJonOssabawIsland,Georgia:the14.WebbPA,HolbrookFR:1989,Vesicularstomatitis.In:Thetruthisoutthere.ProcSocTropVetMed1999:131.arboviruses:epidemiologyandecology,ed.MonathTP,vol.5,13.VanleeuwenJA,Rodrı´guezLL,Wal

2、tner-ToewsD:1995,Cow,pp.223.CRCPress,BocaRaton,FL.farmandecologicriskfactorsofclinicalvesicularstomatitison15.OfficeInternationaldesEpizooties.2001,WorldAnimalHealthCostaRicandairyfarms.AmJTropMedHyg53:342350.in2000.Paris,France.JVetDiagnInvest14:441444(200

3、2)Entericcoronavirusinfectioninajuveniledromedary(Camelusdromedarius)ArnoWu¨nschmann,RodneyFrank,KemPomeroy,SanjayKapilAbstract.Acaseofanentericcoronavirusinfectionina6-week-olddromedarycalfisdescribed.Theanimalhaddiarrheafor5daysanddieddespitesymptomatict

4、reatment.Numerousviralparticles,approximately140nmindiameter,withclub-likeprojectionsweredetectedinthefecesbyelectronmicroscopy.Thesechar-acteristicswereconsistentwithacoronavirus.Immunohistochemicalreactivitywith2antigenicgroupIIco-ronavirus-specificantibo

5、diesconfirmedthepresenceofviralantigenincolonicepithelialcells.ThedeathoftheanimalwasattributedtoaneutrophilicandemphysematouscolitisthatlikelywascausedbyaninfectionwithaClostridiumsp.A6-week-oldfemaledromedary(Camelusdromedarius)minute;referencerange7:4050

6、beats/minute).Thewhitecalfwithahistoryofacutediarrheadied5daysafterthebloodcellcountwas16,000leukocytes/ml(referenceinitialsymptoms.Accordingtotheowner,thecalfwasbornrange13:13,00024,000)withneutrophilia(83%;referenceinMissourionapasturethatwasalsoinhabite

7、dbyzebras.range13:5374%).Theanti-inflammatoryandantibioticThecamelnursedfromitsmotherfor1weekafterbirth.Attreatmentwascontinuedbutthecalfdiedandwassubmitted1weekofage,thecalfwasseparatedfromitsmotherandtotheDepartmentofVeterinaryDiagnosticMedicine,Uni-shipp

8、edtoafarminWisconsin.Uponarrival,thecalfwasversityofMinnesota,St.Paul,Minnesota,forpostmortemcontainedindoorsandinitiallyfedapproximately1literofexamination.Tissuesamples,includingsmallandlargein-warmcalfmilk