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1、17.65%、98.98%>0.62；行醋酸、碘染色后肉眼观察，以上各指标分别为62.5%、87%、13.00%、37.50%>14.71%、98.48%、0.49。敏感度及特异度由高至低依次为TCT、HPV-DNA、VIA+VILIo结论：1、本研究中粤北山区妇女宫颈癌及癌前病变的现患率为3.46%,该人群中瑶族及汉族两民族妇女宫颈癌及癌前病变的现患率无显著性差异。2、TCT检查无论灵敏度及特异度均较高，可作为宫颈癌筛查的较好方法；HPV检测作为宫颈癌病因学检查，可作为宫颈癌及癌前病变初筛的有效方法，适合用于临床病例的检测和指导治疗；肉
2、眼观察法灵敏度及特异度虽低于TCT及HPV检查，但由于其费用低廉、技术含量低，易于培训,可作为经济相对落后的地区的筛查工具。关键词:宫颈癌;宫颈癌前病变；细胞学；HPV-DNA检测AbstractObjective:ToevaluatethesignificanceofHPV-DNAandTCTtesting>visualinspectioninprimaryscreeningofcervicalcanceranditsprecancerouslesionsinnorthernGuangdong5smountainousareas,top
3、rovidereferenceforcervicalcancerpreventioninnorthernGuangdong.Methods:AllsubjectscamefromNorthernGuangdong.Collectedthecervicalexfoliatedcells,andallcytologicalspecimensweredetectedbyTCT>HPV-DNAtestingandvisualinspection.Requiredforfurthercolposcopycheckingandhistopatholo
4、gicalexamination.PreliminaryanalysistheprevalenceinNorthernGuangdong.AllusedSPSS13.0todealtwiththedata.Sensitivity,specificity,positivepredictivevalue,negativepredictivevalueraccuracy,youden'sindexwerecalculated.Thestatisticalsignificaiicewasassessedbychi-squaretest,P<0.0
5、5.ResuIts:1、ThiscrowdparticipatesinprimaryscreeninghadnopatientofCervicalCancer,hadonepatientofCINI,hadtwopatientsofCINII,hadfivepatientsofCTNTTTeTnthisstudy,it'snotstatisticallysignificantoftheprevalenceratebetweenYaoandHanwomen.2>ThepositiveratesofTCTtestinginprimaryscr
6、eeningwas10.39%,thenumberofASCUSaccountingfor7.79%ofthetotalnumber.Theinfectionratesofhumanpapillomaviruswas14.72%.Inthisstudy,it"snotstatisticallysignificantoftheinfectionratesofhumanpapillomavirusbetweenYaoandHanwomen.Thepositiveratesofvisualinspectioninprimar}^screenin
7、gwas14.72%.3>TheinfectionratesofhumanpapillomavirusandthepositiveratesofTCTandVIA>VILIincreasedgraduallywiththeseverityofcervicallesions.4>ThesensitivityofTCTfordetectiiigcervicalcanceranditshighPrecancerous1esionwas87.5%,specificity92.38%.ThesensitivityofI1PVwas75%,speci
8、ficity87.44%.ThesensitivityofVIAandVILIwas62.5%,specificity87%.Thesensitivityandthespecificityof
