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1、内镜下套扎术联合药物治疗食管静脉曲张出血的效果［摘要］目的探讨食管静脉曲张出血行内镜下套扎术联合药物治疗的效果。方法选择2011年10月〜2013年10月在浙江省湖州市中心医院诊治的食管静脉曲张出血患者124例，按照随机数字表法分成两组，每组各62例，对照组予以内镜下套扎术联合常规止血抗炎药物治疗，研究组予以内镜下套扎术与泮托拉哩、生长抑素、普蔡洛尔等联合药物治疗，分析不同分级的再出血、两组止血效果、并发症情况。结果不同Child-Pugh分级再出血率比较，Child-PughC级明显高于Child-PughA及B组，差异有统
2、计学意义(P<0.05)。且研究组出血再发率为3.23%,复发率为6.45%,比对照组(19.35%、24.19%)降低，差异有统计学意义(P<0.05)o同时研究组伴发食管溃疡、门脉高压胃病发生率为3.23%、3.23%,比对照组(19.35%、20.97%)降低,差异有统计学意义(P<0.05)o结论针对食管静脉曲张出血患者，予内镜下套扎术与联合药物治疗，患者的止血效果良好，且并发症较少，具有一定临床应用和研究价值。［关键词］食管静脉曲张出血；内镜下套扎术；效果［中图分类号］R575.2E文献标识码］A［文章编号］1673
3、-7210(2014)06(b)-0031-04TheefficacyofcombiningendoscopicloopingligaturewithdrugforesophagealvaricesbleedingLILilCHENJielLIUChunyanlZHANGJuniLIFeifei21.DepartmentofGastroenterology,HuzhouCentralHospital,ZhejiangProvince,Huzhou313000,China;2.DepartmentofGastroenterolo
4、gy,theAffiliatedHospitalofInnerMongoliaMedicalUniversity,InnerMonggolAutonomousRegion,Huhhot010059,China[Abstract]ObjectiveToexploretheefficacyofcombiningendoscopicloopingligaturewithdrugtoesophagealvaricesbleeding.MethodsFromOctober2011toOctober2013inHuzhouCentralH
5、ospitalofZhejiangProvince,124patientswithesophagealvaricesbleedingwererandomlyselectedandtheseweredividedintot.wogroupsaccordingtorandomnumbertablemethod,62casesweretreatedwithendoscopiclooping1igaturecombinedroutinehemostaticanti-inflammatorydrugsasexperimentgroup,
6、suchasPantoprazole,somatostatinandNaphthalene,thecontrolgroupweredonewithordinarymethods・Thedifferentoftwogroupsonclassificationofbleeding,hemostaticeffectandcomplicationswereanalyzed.ResuItsThedifferentcomparisonofChi1d-Pughforgradingandbleedingrate,Chi1d-PughCgrad
7、ewasobvioushigherthanChild-PughAandBgradewithstatisticalsignificance(P<0.05).Andbleedingofexperimentgroupwas3.23%,whichwaslessthanthecontrolgroup(19.35%);relapserateofexperimentgroupwas6.45%,whichwaslessthanthecontrolgroup(24.19%)withstatisticalsignificanee(P<0.05).
8、Atthesametimetheexperimentgroupwithesophagealulcers,portalhypertensiongastropathywere3.23%and3.23%,thecontrolgroupwere19.35%and20.97%,ther
