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《李兴文 盐酸氟桂利嗪联合阿司匹林治疗偏头痛疗效观察及对脑血流动力学的影响.doc》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、盐酸氟桂利嗪联合阿司匹林治疗偏头痛的疗效及对脑血流速度的影响姓名李兴文单位阳谷具屮医院内科邮编252300［摘要］目的：观察和分析盐酸氟桂利嗪联合阿司匹林治疗偏头痛的疗效及对脑血流速度的影响。方法：选取100例原发性偏头痛患者作为研究对彖，将其随机分为观察组和对照组,每组乞50例。对照组患者给予口服盐酸氟桂利嗪和维生索B1治疗，观察组患者在对照组疗法基础上加用口服阿司匹林肠溶片治疗。对两组患者治疗前、品的头痛积分、双侧犬脑前动脉（ACA）、大脑屮动脉（MCA）、大脑后动脉（PCA）、椎动脉（VA）及基底动脉（BA）的平
2、均血流速度（Vm）进行检测和比较；对两组的临床疗效和临床有•效率进行评价和比较。结果：观察组患者治疗麻的头痛评分显著低于对照纟R（L3.615,P<0.05）,观察纟fl的疗效分布显著优于对照组且临床有效率显著高于对照组（U=2.836,%2=10.981,P<0.05）,观察纟H•患者治疗后的ACA、MCA、BA的Vm均显著低于对照组（t=4・755、5.027、4.169,P<0.05）o结论：M用盐酸氟桂利嗪联合阿司I儿林治疗偏头痛，可冇效缓解想者的头痛症状，提高治疗的临床疗效，降低患者的脑血流速度，冇•利丁•延
3、缓疾病的进展和复发。［关键词］盐酸氟桂利嗪；阿司匹林；偏头痛；疗效观察；脑血流速度TherapeuticeffectsofFlunarizinehydrochloridecombinedwithaspirininthetreatmentofmigraineanditseffectsonthecerebralbloodflowvelocity[Abstract]Objective:ToobserveandanalyzethetherapeuticeffectsofFlunarizinehydrochloridecombi
4、nedwithaspirininthetreatmentofmigraineanditseffectsonthecerebralbloodflowvelocity.Methods:100casesofpatientswithprimarymigrainewereselectedastheresearchobjectsandrandomlydividedintotheobservationgroupandthecontrolgroup・50caseswereincludedintoeachgroup・Thepatient
5、sinthecontrolgroupweretreatedwithoralflunarizinehydrochlorideandvitaminBltherapy,whilethepatientsintheobservationgroupweretreatedwithcombinedoralaspirintherapyonthebasisofthetherapyofthecontrolgroup・Theheadachescore,themeanbloodflowvelocity(Vm)ofbilateralanterio
6、rcerebralartery(ACA)，middlecerebralartery(MCA),posteriorcerebralartery(PCA),vertebralartery(VA)andbasilarartery(BA)ofthepatientsinthetwogroupsbeforeandafterthetreatmentweredetectedandcompared;Thetherapeuticeffectsandtheclinicalefficiencyofthetwogroupswereevaluat
7、edandcompared.Results:Theheadachescoreofthepatientsintheobservationgroupafterthetreatmentwassignificantlylowerthanthatinthethecontrolgroup(t=3・615,P<0.05).Thedistributionoftherapeuticeffectsoftheobservationgroupwassignificantlybetterthanthatofthecontrolgroupandt
8、heclinicalefficiencywassignificantlyhigherthanthatofthecontrolgroup(U=2.836,%2=10.981,P<0.05),TheVmofACA,MCA,BAofthepatientsintheobservationgroupafterthetreatmentwere
