李兴文--盐酸氟桂利嗪联合阿司匹林治疗偏头痛疗效观察及对脑血流动力学的影响

《李兴文--盐酸氟桂利嗪联合阿司匹林治疗偏头痛疗效观察及对脑血流动力学的影响》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、盐酸氟桂利嗪联合阿司匹林治疗偏头痛的疗效及对脑血流速度的影响姓名李兴文单位m谷县中医院内科邮编252300I摘要j目的：观察和分析盐酸氣桂利嗪联合阿司匹林治疗偏失痛的疗效及对脑血流速度的影响。方法：选取100例原发性偏头痛患者作为研究对象，将其随机分为观察绀和对照自I,每组各50例。对照组患者给予口服盐酸氟桂利嗪和维生素B1治疗，观察组患者在对照组疗法葙础上加用口服阿司匹林肠溶八治疗。对两组患者治疗前、盾的头痛积分、双侧大脑前动脉（ACA）、人脑屮动脉（MCA）、人脑后动脉（PCA）、椎动脉（VA）及基底动脉（BA）的T•均血流速度（Vm）进行检测和比较；对两组的临床疗效和临床有效率

2、进行评价和比较。结果：观察飢患者治疗后的头痛评分显著低于对照纟II（t=3.615,P<0.05）,观察纽的疗效分布显著优于对照组且临床有效率显著商于对照组（U=2.836,%2=10.981,P<0.05）,观察组患者治疗后的ACA、MCA、BA的Vm均显著低于对照组（t=4.755、5.027、4.169,P<0.05）。结论：应用盐酸氟桂利嗪联合阿司匹林治疗偏1•痛，可有效缓解患者的尖痛症状，提高治疗的临床疗效，降低患者的脑血流速度，冇利于延缓疾病的进展和复发。［关键词］盐酸氟桂利嗪；阿司匹林；偏头痛；疗效观察；脑血流速度TherapeuticeffectsofFlunariz

3、inehydrochloridecombinedwithaspirininthetreatmentofmigraineanditseffectsonthecerebralbloodflowvelocity[Abstract]Objective:ToobserveandanalyzethetherapeuticeffectsofFlunarizinehydrochloridecombinedwithaspirininthetreatmentofmigraineanditseffectsonthecerebralbloodflowvelocity.Methods:100casesofpa

4、tientswithprimarymigrainewereselectedastheresearchobjectsandrandomlydividedintotheobservationgroupandthecontrolgroup.50caseswereincludedintoeachgroup.ThepatientsinthecontrolgroupweretreatedwithoralflunarizinehydrochlorideandvitaminBItherapy，whilethepatientsintheobservationgroupweretreatedwithco

5、mbinedoralaspirintherapyonthebasisofthetherapyofthecontrolgroup.Theheadachescore，themeanbloodflowvelocity(Vm)ofbilateralanteriorcerebralartery(ACA)，middlecerebralartery(MCA),posteriorcerebralartery(PCA)，vertebralartery(VA)andbasilarartery(BA)ofthepatientsinthetwogroupsbeforeandafterthetreatment

6、weredetectedandcompared;Thetherapeuticeffectsandtheclinicalefficiencyofthetwogroupswereevaluatedandcompared.Results:Theheadachescoreofthepatientsintheobservationgroupafterthetreatmentwassignificantlylowerthanthatinthethecontrolgroup(t=3.615，P<0.05).Thedistributionoftherapeuticeffectsoftheobserv

7、ationgroupwassignificantlybetterthanthatofthecontrolgroupandtheclinicalefficiencywassignificantlyhigherthanthatofthecontrolgroup(U=2.836,X2=10.981,P<0.05),TheVmofACA,MCA,BAofthepatientsintheobservationgroupafterthetreatmentweresig