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1、中国热带医学2017年第17卷第4期ChinaTropicalMedicine,April2017,Vol.17,No.4·411··短篇论著·早中孕期胎儿畸形超声筛查方法分析徐世亮,宝波,李娜,魏珊,杨暖中南大学湘雅医学院附属海口医院,海南海口570208摘要:目的探讨二维超声和二维联合实时三维超声在孕早中期筛查胎儿畸形的价值,为临床推广无创伤筛查方法提供基础资料依据。方法回顾性分析中南大学湘雅医学院附属海口医院于2013年1月—2015年6月共4929例产妇经产前二维超声和二维联合实时三维超声对比检查结果,并对比分析追踪引产或分娩的结
2、果。结果引产或分娩后证实胎儿畸形151例,二维超声检出的胎儿畸形108例,准确率为71.5%,二维超声联合实时三维超声检出胎儿畸形135例,准确率为89.4%,差异有统计学意义(P<0.05)。二维超声联合实时三维超声在胎儿神经系统畸形、先天性心脏畸形、消化道畸形、唇腭裂、两种及以上多种畸形等的检出准确率要明显高于单独使用二维超声,差异有统计学意义(P<0.05)。结论二维超声联合实时三维超声检查可以明显提高胎儿畸形的筛查率,有助于优生优育。关键词:二维超声;实时三维超声;早中孕期;胎儿畸形中图分类号:R714.43文献标识码:B文章编号
3、:1009-9727(2017)04-411-03DOI:10.13604/j.cnki.46-1064/r.2017.04.23UltrasoundscreeningmethodinfetalmalformationoftheearlyandmiddlepregnancyXUShiliang,BAOBo,LINa,WEIShan,YANGNuanHaikouHospitalAffiliatedtoXiangyaMedicalSchoolofCentralSouthUniversity,Haikou,Hainan570208,ChinaA
4、bstract:ObjectiveToanalyzeandexplorethevalueoftwo-dimensionalultrasoundandtwo-dimensionalultrasoundcombinedwiththree-dimensionalultrasoundinearlyandmiddlepregnancyfetalmalformationscreening,weprovidebasicdataforpromotingnon-invasivescreeningmethodinclinic.MethodsToretrosp
5、ectivelyanalyzetheresultofobstetrical4929casesbyusingtwo-dimensionalultrasoundandtwo-dimensionalultrasoundcombinedwiththree-dimensionalultrasound,tocontrast,weanalyzedandfollowedtheresultofinducedabortionordelivery.ResultsAmongthe4929obstetricalcases,thefetalmalformations
6、wereconfirmed151cases,108fetalmalformationswerefoundbysingletwo-dimensionalultrasound,butafterinducedabortionanddelivery,thediagnosticaccuracywas71.5%,while135fetalmalformationswerefoundbycombineddetection,thediagnosticaccuracywas89.4%.Thedifferencewasstatisticallysignifi
7、cant(P<0.05).Thediagnosticaccuracyofthefetalmalformation,suchasneuralmalformation,congenitalheartmalformation,digestivetractmalformation,cleftlipandpalate,byusingcombineddetectionwassignificantlyhigherthansingletwo-dimensionalultrasound.Thedifferencewasstatisticallysignif
8、icant(P<0.05).ConclusionTwo-dimensionalultrasoundcombinedwiththree-dimensionalultrasoundcanmarke