[精品][经典]双水平气道正压通气治疗中晚期妊娠重度哮喘的临床研究.doc

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1、[经典]双水平气道正压通气治疗中晚期妊娠重度哮喘的临床研究双水平气道正压通气治疗中晩期妊娠重度哮喘的临床研究【摘耍】目的研究无创通气在中晩期妊娠重度哮喘治疗中对胎儿、动脉血气指标（pH、PaO₂>PaC0₂>Sa0_{2心率（HR）和呼吸频率（RR）的影响。方法将30例中晚期妊娠重度支气管哮喘患者随机分为无创通气（双水平鼻/面罩NIPPV）+药物治疗组（实验组15例）和对照组（15例）。比较治疗后两组动脉血气指标（pH、Pa02>PaC0}

2、b>2>Sa0₂

3、d—latepregnancyLTANGXiong,LTHui,ZHANGXue-wen.DepartmentofRespiratoryMedicine,TheAffi1iatedBaoanHospitalofNanfangMedicalUniversity,GusngdongProvince518101,China[Abstract]ObjectiveTostudytheclinicalvalueofbi~Ievelpositiveairwaypressure（BiPAP）venti1ationintreatmentofsev

4、ereasthmainmid-latepregnancy:inf1tieneeofthefoetus,changesofpH,Pa0₂,PaC0₂,Sa0₂inthearterialbloodgas,heartrate（HR）andrespiratoryrate(RR)・MethodsThirtycasesofsevereasthmainmid-latepregnancywererandomlydividedintotwogroups・Onegroupweretr

5、eatedbydrugs(controlgroup),theothergroupweretreatedbynoninvasivepositivepressureventilation(NIPPV)andthedrugs(experimentgroup)with15casesineachgroup.TheexperimentgroupwastreatedwithBiPAPventilationviafacial(nasal)mask.Thecomparisonwasmadeonthechangesofthearterialbloo

6、dgasbeforeandafterthetreatmentbetweentwogroups.Andalsoinfluenceofthefoetus,thechangesofclinicalsymptom,HRandRRwereobtainedbeforetreatment.ResultsSignificantdifferenceswerefoundintheexperimentgroupoftheimprovementofPa0₂,PaC0₂,Sa0₂,HR,R

7、R,comparedwiththoseofthecontrolgroup(P<0.01).ConclusionOnthefoundationofconventionalmedicinecure,double-levelnasalmask/maskventilationmodeisusedforthetreatmentofsevereasthmainmid-latepregnancy,anditcaneffectivelyreducetrachealintubationrateandinfluenceofthefoetus・[Ke

8、ywords】Non-invasiveventilation；Severeasthmaduringpregnancy；Bloodgasanalysis妊娠合并哮喘的发病率已由十年前的0.4%〜1%逐年攀升至3.7%、8・4%^[l],近年来还