Hepatitis B.ppt

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1、HepatitisBdemi邓Originallyknownas"serumhepatitis(血清性肝炎）",thediseasehascausedepidemics（inpartsofAsiaandAfrica,anditisendemicinChina.Aboutaquarteroftheworld'spopulation,morethan2billionpeople,havebeeninfectedwiththehepatitisBvirus.Thisincludes350millionchroniccarri

2、ers（长期带菌者）ofthevirus.地理分布HBsAgPrevalence³8%-High2-7%-Intermediate<2%-LowTransmissionConcentrationofHBVinVariousBodyFluidsLow/NotHighModerateDetectablesemenserumvaginalfluidbloodwoundexudatessalivaurinefecessweattearsbreastmilkTransmissionmaternal-neonataltransmi

3、ssionWithoutintervention,amotherwhoispositiveforthehepatitisBsurfaceantigenconfersa20%riskofpassingtheinfectiontoheroffspringatthetimeofbirth.Thisriskisashighas90%ifthemotherisalsopositiveforthehepatitisBantigen.sexualcontactRoughly16-40%ofunimmunizedsexualpartn

4、ersofindividualswithhepatitisBwillbeinfectedthroughsexualcontact.symptomsFatigue,malaise,jointaches,andlow-gradefeverabdominalpain,vomiting,lossofappetite,Jaundice(yellowskinandeyes)liverswellingdarkurineduetoincreasedbilirubinComplications*Chronichepatitis*Cirr

5、hosis*HepatocellularcarcinomaTreatmentvaccinationTheinfectionofHBVcanbepreventablebyvaccination.LAM(lamivudine)RestBedresttillLFTnormalandlast6monthsaccordingtonopathologicalchangeDiettherapyHighcarbohydratediet,highcalorieNoalcoholLowfat,moderateprotein,Smallfr

6、equentmealsVitB,C,K.drugliverprotectantDrugs:silybin水飞蓟素hemostaticDrugs：VitaminsespeciallyKparental,Reptilase立止血cutdownjaundiceDrugs:Potassiummagnesiumaspartate门冬酸钾镁PatienteducationPreventiontohealthcareprofessionalsKnowledgeoftransmissionroutesProperpersonalhyg

7、ieneandgoodsanitationSafetySex