欢迎来到天天文库
浏览记录
ID:48007282
大小:874.96 KB
页数:4页
时间:2020-01-12
《黏液纤维肉瘤的MRI表现与组织病理学对照.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、216放射学实践2011年2月第26卷第2期RadiolPractice,Feb2011,Vol26,No.2骨骼肌肉影像学黏液纤维肉瘤的MRI表现与组织病理学对照马小龙,汪建华,陆建平,刘崎,白晨光【摘要】目的:探讨黏液纤维肉瘤(MFs)的MRI表现与组织病理学的联系。方法:回顾性分析8例经手术病理证实的MFS(低度恶性4例,中度恶性2例和高度恶性2例)临床、MRI及病理资料。结果:MRI表现:除1例高度恶性MFS位置较深外,其余7例均较袁浅;肿瘤体积较大,平均5.0cm×7.5cm;3例MFS(1例中度恶性,2例高度恶性)分叶明显,与周围组织分界不清,余5例分
2、叶不明显,与周围组织分界清楚;8例MFS内部信号均较混杂,增强后强化不均,低度及中度恶性MFS示强化区与无强化区交织分布,高度恶性MFs示明显结节样强化区及无强化区。病理表现:MFS内部存在黏液样基质占优势的细胞疏松区和肿瘤细胞占优势的细胞密集区,其中低度恶性肿瘤边界清晰,膨胀性生长,内部含有明显占优势的黏液样基质和少量细胞密集区,呈交替分布;而高度恶性肿瘤呈浸润性生长,边界不清晰,有较多的结节样的细胞密集区;_中度恶性肿瘤生长方式与形态介于前两者之间。结论:MFS的MRI表现与其组织病理学密切相关,MRI显示MFS的侵袭范围及周围卫星灶可为其病理分级提供影像学支
3、持。【关键词】软组织肿瘤;纤维肉瘤;磁共振成像;病理学【中图分类号】R738.6;R445.2【文献标识码】A【文章编号】1000—0313(2011)020216一O4CorrelationofMRIimagingfeaturesandhistopathologyofMyxofibrosarcomaMAXiao—long,WANGJianhua,LUJian—ping,eta1.DepartmentofRadiology,ChanghaiHospital,SecondMilitaryMedicalUniversity,Shanghai200433,P.R.Chi
4、na[Abstract]Object:Toexplorethefeaturesofmyxofibrosarcoma(MFS)onMRIandcorrelationwithhistopathology.Methods:Clinicalrecords,MRIandhistOpathologydataof8casesofMrS(1ow—grade4,intermediategrade2andhigh—grade2)confirmedbysurgeryandpathologywereretrospectivelyanalyzed.Results:MRI:excepttha
5、tonecaseofhighgradetumorlocatedinthedeeplayer,theother7caseswerelocatedinthesuperficiallayer.Alltuorshadhugevolume,theaveragediameterwas5.0cm×7.5cm.3cases(1intermediate~gradetumorand2highgradetumors)hadmarkedlobulation,andtheirborderswithsurroundingtissueswereunclear,theothers5casesha
6、dwell—definedmarginandnodefinitelobulation.AlltumorsshowedmixedinnersignalsandwereenhancedinhomogeneouslyonMR1.ThelowgradeandintermediategradeMFSshowedamixeddistributionofareasofenhancementandnonenhancement.ThehighgradeMFSshowedenhancednodularareaandnonenhancedarea.Histopathology:MFSc
7、onsistedofhypocellularmyxoidmatrixandhypercellulararea.Thelow—gradeMFSshowedexpansivegrowthwithclearborder,andhypocellulartomoderatelycellulararchitecturewithapredominantmyxoidmatrix;Thehigh—gradeMFSshowedinvasivegrowthwithunclearborder,andmoresolidhypercellulararchitecturewithasmallm
8、yxoid
此文档下载收益归作者所有