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1、MicrocrystallineCelluloseCellulose[9004-34-6].DEFINITIONMicrocrystallineCelluloseispurified,partiallydepolymerizedcellulosepreparedbytreatingalphacellulose,obtainedasapulpfromfibrousplantmaterial,withmineralacids.IDENTIFICATION•A.ProcedureIodinatedzincchloridesolu
2、tion:Dissolve20gofzincchlorideand6.5gofpotassiumiodidein10.5mLofwater.Add0.5gofiodine,andshakefor15min.Sample:10mgAnalysis:PlacetheSampleonawatchglass,anddispersein2mLofIodinatedzincchloridesolution.Acceptancecriteria:Thesubstancetakesonaviolet-bluecolor.氯化锌碘试液：取氯
3、化锌20g、碘化钾6.5g，加水10.5ml。再加碘0.5g，振摇15min。测定：取本品10mg，置表面皿上，加氯化锌碘试液2ml。标准规定：应变为蓝紫色。Changetoread:•B.ProcedureSample:1.3gofMicrocrystallineCellulose,accuratelyweighedto0.1mgAnalysis:TransfertheSampletoa125-mLconicalflask.Add25.0mLofwaterand25.0mLof1.0Mcupriethylenediami
4、nehydroxidesolution.Immediatelypurgethesolutionwithnitrogen,insertthestopper,andshakeonawrist-actionshaker,orothersuitablemechanicalshaker,untilcompletelydissolved.TransferanappropriatevolumeoftheSamplesolutiontoacalibratednumber150Cannon-Fenske,orequivalent,visco
5、meter.Allowthesolutiontoequilibrateat25±0.1forNLT5min.Timetheflowbetweenthetwomarksontheviscometer,andrecordtheflowtime,t1,ins.取本品1.3g，精密称定，置125mL具塞锥形瓶中，精密加入水25ml，再精密加入1mol/L双氢氧化乙二胺铜溶液25ml，立即通入氮气以排除瓶中空气，密塞，强力振摇，使微晶纤维素溶解；取适量，置25±0.1℃水浴中，约5min后，移至刻度为150的坎农-芬斯克毛细管粘度计
6、或同等的黏度计内（毛细管内径为0.7~1.0mm，选用适宜粘度计常数K1），照黏度测定法，于25±0.1℃水浴中测定。记录供试品溶液流经黏度计上下两刻度时的时间t1，按下式计算供试品溶液的运动黏度。Calculatethekinematicviscosity,(KV)1,oftheMicrocrystallineCellulosetaken:微晶纤维素的运动黏度(KV)1按下式计算：Result=t1×k1t1=flowtime(s)k1=viscometerconstant(seeViscosity—CapillaryM
7、ethods911(CN1-May-2015))Obtaintheflowtime,t2,for0.5Mcupriethylenediaminehydroxidesolutionsusinganumber100Cannon-Fenske,orequivalent,viscometer.用刻度为100的坎农-芬斯克毛细管粘度计或同等的黏度计测定0.5M双氢氧化乙二胺铜溶液流经黏度计上下两刻度时的时间t2，按下式计算空白溶液的运动黏度。Calculatethekinematicviscosity,(KV)2,ofthesolv
8、ent:空白溶液的运动黏度(KV)2按下式计算：Result=t2×k2t2=flowtimefor0.5Mcupriethylenediaminehydroxidesolutions(s)t2=0.5M双氢氧化乙二胺铜溶液流经黏度计上下两刻度时的时间(s)k2=viscometerconstantk2
