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1、青年人结直肠癌101例临床病理特征分析作者:贾兴芳刘成霞作者单位:滨州医学院附属医院消化内科滨州市256603【摘要】冃的探讨青年人结直肠癌临床特点与病理学特征。方法收集我院1996年1月—2007年12刀间手术的101例青年结直肠癌患者的临床及病理资料,进行总结分析。结果101例青年结直肠癌患者中,误诊63例,误诊率达62.3%,误诊以肠炎、痔疮、痢疾多见;其发病部位以直肠最多,41例(40.6%)淇次为乙状结肠,18例(17.8%);降结肠最少,4例(3.9%);病理类型以管状腺癌、黏液腺癌多见,占73.
2、3%;Dukes分期其中C+D期为主,56例,占55.4%。结论青年结直肠癌恶性程度高,误诊率高,预后差,早期行直肠指检对发现直肠癌有重要作用;电了结肠镜检查可及早诊断结直肠癌的癌前病变并适时进行干预,从而大大降低了结直肠癌的发生率,为治疗及预后评估提供重要依据。【关键词】结直肠癌;青年人;临床特征;病理特征Clinicalpathologicalcharacteranalysisin101casesofyoungpatientswithcolorectalcancerJIAXingfangLIUChengxiaDepa
3、rtmentofGastroenteropathy,AffiliatedHospitalofBinzhouMedicalUniversity,Binzhou256603【Abstract】ObjectiveTostudytheclinicalpathologicalcharacterin101casesofyoungpatients(age<40)withcolorectalcancer.MethodsApplyingstatisticmethods,weanalyzedtheclinicalpathologicalfe
4、atureof101casesofyoungpatientswithcoloncancerwhohavebeenoperatedinhospitalfromJanuary1996toDecember2007.ResultsSixtythreeof101weremisdiagnosedinthisgroup.Themisdiagnosisratewas62.3%・Theywereoftenmisdiagnosedasbacillarydysentery,hemorrhoidandenteritis.Inthisgroup,
5、rectalcancerwasthemost(40.6%),followedbysigmoidcoloncancer(17.8%),descendingcoloncancerscarcely(3.9%).Theproportionofadenocarcinomaandmucinouscarcinomawas73.3%.DukesstagesCandDwasnotedin56cases(55.4%).ConclusionTheyoungpatienswithcolorectalcancerhavethecharacteri
6、sticofhighmisdiagnosisrate,highincidenceofpoordifferentiation,moreadvancedstagesandpoorprognosis.Itisimportanttodigitalrectalexamineforcolorectalcance匚Colonoscopeexaminingcandiagnoseprecancerouslesionearlyandinterfereitinevolvingattherightmoment,sothatcanreduceth
7、eincidenceofcolorectalcancer.Allcanprovideimportantevidencefortreatmentandprognosisappraisal.【Keywords】colorectalcancer,young,clinical,pathologicalcharacter结直肠癌(colorectalcancer)是临床常见的恶性肿瘤之一,是西方国家笫2位高发恶性肿瘤[1]。近年來,结直肠癌的发病率呈逐年增加的趋势,特别是青年人[2](<40岁)结直肠癌。青年人结直肠癌具有症状隐匿
8、、发展快、浸润转移早、恶性程度高、误诊率高等特点,待确诊时多已属晚期。现将我院1996年1月—2007年12月行手术治疗的101例青年人结直肠癌做一分析,旨在进一步探讨青年人结直肠癌的临床特点及病理学特征。1临床资料1.1一般资料木资料中男60例,女41例,男女比为1.5:lo年龄12〜40岁,平均年龄3