宫颈液基细胞学检查在宫颈病变诊断中的应用价值

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1、宫颈液基细胞学检査在宫颈病变诊断中的应用价值［摘耍］冃的探讨宫颈液基细胞学对CIN诊断的临床价值。方法回顾性分析2008年12月〜2010年12月346例忠者行阴道镜宫颈活组织检杳结果异常的临床资料。检杏结果以病理结果为金标准进行分析。结果173例ASC-US••诊断为C1N86例，与宫颈活检符合率为49.7%(CINI71例，CINII11例，CINIII4例)；诊断为浸润癌1例,与宫颈活检符合率为0.6%。25例ASC-H中诊断为CTN18例，与宫颈活检符合率为72.0%。105例LSL中诊断为CIN72例,

2、与宫颈活检符合率为68.6%o43例IISL中诊断为C1N33例,与宫颈活检符合率为76.7%；诊断为浸润癌5例，与宫颈活检符合率为11.6%。结论宫颈液基细胞学是宫颈癌前病变简单冇效的诊断方法，值得临床推广应用。［关键词］宫颈液垄细胞学；阴道镜检查；宫颈上皮内瘤变；病理；早期筛查［中图分类号］R737.33［文献标识码］B［文章编号］1673-9701(2012)06-0135-02ValueofIiquid-basedcervicalcytologyinthediagnosingforcervicalintr

3、aeithelialneoplasiaZHANGYanDepartmentofGynecologyandObstetrics,MaternalandChildHea1thHospitalinthePudongNewArea,Shanghai201206,China［Abstract］ObjectiveTostudyonvalueof1iquid-basedcervicalcytologyinthediagnosingforcervicalintraeithelialallneoplasia(CIN)・Method

4、sTheclinicaldataof346casesfromDecember2008toDecember2010wasanalyzedretrospectively,andallthepatientsweregiventhetestliquid-basedcervicalcytologycombinedwithcervicalbiopsyhistopathology.Theresultsofliquid-basedcervicalcytologywasjudgedthroughthepathologyresult

5、sasthegoldstandard・ResultsTherewere86casesCINpatientsamong173caseswithASC-USpatients,thecomplianeeratewiththepathologywas49.7%(71casesCTNI,11casesCTNIIand4casesCTNIII)and1caseswasdiagnosedinvasivecarcinoma.Therewere18casesCINpatientsamong25caseswithASC-Hpatie

6、nts,thecomplianceratewiththepathologywas72.0%・Therewere72casesCINpatientsamong105caseswithLSLpatients,thecomplianeeratewiththepathologywas68.6%・Therewere33casesCTNpatientsamong43caseswithHSLpatients,thecomplianceratewiththepathologywas76・7%.5caseswasdiagnosed

7、invasivecarcinoma,thecomplianeeratewiththepathologywas11.6%.ConclusionTheliquid-basedcervicalcytologyissimpleandeffectivediagnosticmethodforthecervicallesionsandisworthyofclinicalapplication.［Keywords］Liquid-basedcervicalcytology;Colposeopy;Cervicalintraeithe

8、lialneoplasia;Pathoiogy;Screenin宫颈病是威胁女性生命健康的第二大恶性肿瘤，仅次于乳腺癌［1］。据世界卫生组织报告显示，我国的宫颈癌以每年2%~3%的速度增长，发生率为14.6/10Jj-，每年人约有5万名女性死于宫颈癌，宫颈癌正成为严重威胁我国女性身心健康疾病Z—［2-3］。宫颈癌是可以经过医学干预而降低发病率和死亡率的恶性肿瘤，是一种町预