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1、微创经皮肾镜取石术治疗输尿管上段嵌顿性结石临床观察[摘要]目的观察微创经皮肾镜取石术(MPCNL)治疗嵌顿性输尿管上段结石的疗效。方法回顾性分析单侧输尿管上段结石伴嵌顿患者115例,根据患者的选择分别采用MPCNL(65例)和经尿道输尿管镜取石术(URL)(50例)治疗,分别对其结石清除率、手术时间、住院时间、术中并发症发生率、术后辅助治疗、术后并发症等数据进行对比分析。结果MPCNL组的术后3d结石清除率为100.00%,而URL组的术后3d结石清除率为62.00%,两组比较差异有统计学意义(P=
2、0)o随访术后1个月的结石清除率,MPCNL组为100.00%,较URL组的84.00%明显提高(P=0.001)。MPCNL组的手术时间(t=5.753,P=0)和住院时间(t=8.635,P=0)较URL组的明显缩短。两组术中并发症、术后感染和血红蛋白下降发生率比较,差异无统计学意义(P>0.05)o而MPCNL组术后辅助体外冲击波碎石术(ESWL)治疗率为1.54%,明显低于URL组的18.00%,差异有统计学意义(P二0.002)o结论MPCNL治疗嵌顿性输尿管上段结石结石清除率高、并发症少
3、、安全有效,可作为嵌顿性输尿管上段结石的首选治疗方法。[关键词]微创经皮肾镜取石术;输尿管镜;输尿管结[中图分类号]R693+.4[文献标识码]A[文章编号]1673-7210(2012)01(c)-0065-03ClinicalobservationofminimallyinvasivepercutaneousnephrolithotomyinthetreatmentofimpactedupperureteralstonesZHANGJiongLANGGenqiangZHANGYifengCHUJ
4、ianZHUANGJianqiuCAOJianweiDepartmentofUrinarySurgery,the411thHospitalofPLA,Shanghai200081,China[Abstract]ObjectiveToexploretheeffectoftheminimallyinvasivepercutaneousnephrolithotomy(MPCNL)inthetreatmentofimpactedupperureteralstones.Methods115casesofofi
5、mpactedupperureteralstoneswerestudiedretrospectively.Accordingtotheselectionofoperation,65caseswereunderwentminimallyinvasivepercutaneousnephrolithotomylithotomy(MPCNLgroup)and50caseswereunderwentureteroscopiclithotripsy(URLgroup).Thestone-freerate,ope
6、rativetime,hospitalstay,incidenceofintraoperativecomplications,postoperativeadjuvanttherapy,postoperativecomplicationsandotherdatawereanalyzed.ResuItsThestone-freerateat3daysfollow-upwas100.00%inMPCNLgroup,62.00%inURLgroup,thediffereneewasstatistically
7、significant(P二0).Thestone-freerateatonemonthfollow-upwas100.00%inMPCNLgroupand84.00%inURLgroup(P=0.001).InMPCNLgrouptheoperativetime(t=5.753,P=0)andhospitalstay(t二8.635,P=0)weresignificantlyshorterthanthoseinURLgroup・Therewerenosignificantdifferencesin
8、theratesofintraoperativecomplications,postoperativeinfectionandhemoglobindeclinebetweenthetwogroups(P>0.05)・InMPCNLgroup,theratesofadjuvantESWLwas1.54%,significantlylowerthan18.00%inURLgroup(P=0.002).ConclusionMPCNLforimpactedupperurete