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1、感染性心内膜炎72例临床分析作者:土国华,秦永文单位:上海宝山中心医院心内科(王国华);上海,第二军医大学长海医院心内科(秦永文)【摘要】目的分析近年來感染性心内膜炎(1E)临床特点的变化。方法冋顾性分析1998年10月—2006年6月住院治疗的72例IE患者的的临床资料,包括血培养、超声检查、手术治疗及预后等资料。结果72例IE患者中,<40岁44例(61.1%),风湿性心脏病37例(51.4%),先天性心脏病16例(22.2%),特发性二尖瓣脱垂及关闭不全13例(1&1%),分别居基础心脏病的前3位。不规则发热53例(73.6%)、
2、心力哀渴26例(36.1%)、跚L18例(25.0%)、脾肿大6例(8.3%).Osler结2例(2.8%)和脑血管意外1例(1.4%)。超声心动图检查发现赘牛物49例(68.1%);细菌培养47例,阳性22例(46.8%),其中致病菌为链球菌16例(34.0%),葡萄球菌4例(8.5%),肠球菌1例(2.1%)、其他细菌1例(2.1%);手术治疗65例(90.3%),住院期间死亡1例(1.4%)。繼IE多见于40岁以下人群,以风湿性心脏病为常见基础心脏病,链球菌是常见致病菌,及时手术能降低住院病死率。【关键词】心内膜炎,感染性;流行病学;临床分析Cli
3、nicalanalysisof72patientswithinfectiousendocarditisWANGGuohua,QINYongwen.DepartmentofCardiology,BaoshanCentralHospital,Shanghai201900,China【Abstract]ObjectiveToevaluatetheclinicalfeaturesofinfectiousendocarditis(IE)inrecentyears.MethodsRetrospectivelyanalysis72caseswithIEfromOctJ
4、998toJun,2006,theindexedincludedclinicalmaterials,bloodculture,ultrasonography,surgeryprocedureandprognosis.ResultsFortyfourcasesof72(61.1%)wasbelow40yearsofage.Rheumaticheartdisease(RHD)was37cases(51.4%),congenitalcardiovasculardiseaseswas16cases(22.2%),idiopathicmitralvalveprol
5、apseandincompetencewas13cases(18.1%).Therewere53cases(73.6%)withirregularfever,26caseswithheartfailure(36」%),18caseswithanemia(25.0%),6caseswithsplenomegaly(&3%),2caseswithOsler'snode(2.8%),and1casewithbrainvascularaccident(1.4%).Theechocardiographyresultsshowedthatvegetationswer
6、epresentin49cases(68.1%).Therewere47caseunderwentbloodculture,andpathogenicbacteriumwasStreptococciin16cases(34.0%),Staphylococciin4cases(8.5%),Enterococcusin1case(2.1%),andothersin1case(2.1%).Therewere65patients(90.3%)underwentcardiacsurgery,andone(1.4%)ofthemdiedduringtherapy.C
7、onclusionItdemonstratedthatIEwascommoninpeoplebelow40yearsold,andrheumaticheartdiseasewasthemostcommonreason.TheStreptococciwasstillthecommonestresponsiblemicroorganisms.EarlyinterventionaltherapycouldbehelpfultoimprovetheoutcomeofIE・【Keywords]Endocarditis,infective;Epidemiology;
8、Clinicalanalysis近20年來,尽管感染性心内膜炎(IE)的发病率变